The effects of human pregnancy-specific β1-glycoprotein preparation on Th17 polarization of CD4+ cells and their cytokine profile

VP Timganova, SA Zamorina, LS Litvinova… - BMC immunology, 2020 - Springer
Background Pregnancy-specific β1-glycoproteins are capable of regulating innate and
adaptive immunity, exerting predominantly suppressive effects. In this regard, they are of …

Effects of pregnancy-specific β-1-glycoprotein on the helper T-cell response

V Timganova, M Bochkova, P Khramtsov… - Archives of Biological …, 2019 - serbiosoc.org.rs
Pregnancy-specific β-1-glycoproteins (PSGs) are capable of regulating innate and adaptive
immunity. As fetal antigens circulate in the blood of pregnant women, it is of particular …

[HTML][HTML] Recombinant pregnancy-specific glycoprotein-1-Fc reduces functional deficit in a mouse model of permanent brain ischaemia

K Malone, JA Shearer, JM Williams, AC Moore… - Brain, behavior, & …, 2022 - Elsevier
Background The well-characterised role of the immune system in acute ischaemic stroke
has prompted the search for immunomodulatory therapies. Pregnancy-specific glycoproteins …

[HTML][HTML] Immunoregulatory potential of pregnancy-specific β1-glycoprotein

VP Timganova, MS Bochkova, MB Rayev… - Медицинская …, 2021 - cyberleninka.ru
The embryo, being half an antigenically “foreign” organism, should elicit a maternal immune
response. During evolution, however, the mechanisms ensuring successful development of …

Иммунорегуляторный потенциал трофобластического β1-гликопротеина

ВП Тимганова, МС Бочкова, МБ Раев… - Медицинская …, 2021 - mimmun.ru
Аннотация Эмбрион, являясь наполовину «чужеродным» в антигенном отношении
организмом, должен вызывать ответную реакцию иммунной системы матери. Однако в …

Expression of pregnancy specific β-1 glycoprotein 1 in cervical cancer cells

M Rodríguez-Esquivel, P Romero-Morelos… - Archives of Medical …, 2020 - Elsevier
Background Cervical Cancer (CC) is a worldwide public health concern associated with
genetic alterations, among these the gain of the 19q chromosome harboring the Pregnancy …

Effect of Short Peptides of Pregnancy-Specific β1-Glycoprotein on Differentiation of Human Regulatory T Cells In Vitro and on Their Cytokine Profile

VP Timganova, MS Bochkova, KY Shardina… - Bulletin of Experimental …, 2024 - Springer
Pregnancy-specific β1-glycoprotein (PSG), one of the most important proteins of pregnancy,
has a pronounced immunosuppressive effect. Short peptides of PSG, the so-called SLiMs …

ВЛИЯНИЕ КОРОТКИХ ПЕПТИДОВ ТРОФОБЛАСТИЧЕСКОГО β1-ГЛИКОПРОТЕИНА НА ДИФФЕРЕНЦИРОВКУ РЕГУЛЯТОРНЫХ Т-КЛЕТОК ЧЕЛОВЕКА IN …

ВП ТИМГАНОВА, МС БОЧКОВА, КЮ ШАРДИНА… - … В БИОЛОГИИ И … - elibrary.ru
Трофобластический β1-гликопротеин (ТБГ), один из ключевых белков беременности,
обладает выраженным иммуносупрессивным эффектом. Короткие пептиды ТБГ, так …

The role of regulatory T cells in stroke recovery

K Malone - 2022 - cora.ucc.ie
Background: Acute ischaemic stroke is a major cause of mortality worldwide. Despite the
search for new therapies, tissue plasminogen activator remains the only FDA-approved …