Molecular basis of bacterial outer membrane permeability revisited

H Nikaido - Microbiology and molecular biology reviews, 2003 - Am Soc Microbiol
Gram-negative bacteria characteristically are surrounded by an additional membrane layer,
the outer membrane. Although outer membrane components often play important roles in …

Invited review: diversity of endotoxin and its impact on pathogenesis

MS Trent, CM Stead, AX Tran… - Journal of endotoxin …, 2006 - journals.sagepub.com
Lipopolysaccharide or LPS is localized to the outer leaflet of the outer membrane and serves
as the major surface component of the bacterial cell envelope. This remarkable glycolipid is …

The PmrA-Regulated pmrC Gene Mediates Phosphoethanolamine Modification of Lipid A and Polymyxin Resistance in Salmonella enterica

H Lee, FF Hsu, J Turk, EA Groisman - Journal of bacteriology, 2004 - Am Soc Microbiol
ABSTRACT The PmrA/PmrB regulatory system of Salmonella enterica controls the
modification of lipid A with aminoarabinose and phosphoethanolamine. The …

Border control: regulating LPS biogenesis

RL Guest, ST Rutherford, TJ Silhavy - Trends in Microbiology, 2021 - cell.com
The outer membrane (OM) is a defining feature of Gram-negative bacteria that serves as a
permeability barrier and provides rigidity to the cell. Critical to OM function is establishing …

Detection of conserved N-linked glycans and phase-variable lipooligosaccharides and capsules from campylobacter cells by mass spectrometry and high resolution …

CM Szymanski, FS Michael, HC Jarrell, J Li… - Journal of Biological …, 2003 - ASBMB
Glycomics, the study of microbial polysaccharides and genes responsible for their formation,
requires the continuous development of rapid and sensitive methods for the identification of …

Lipopolysaccharide inner core oligosaccharide structure and outer membrane stability in human pathogens belonging to the Enterobacteriaceae

E Frirdich, C Whitfield - Journal of endotoxin research, 2005 - journals.sagepub.com
In the Enterobacteriaceae, the outer membrane is primarily comprised of
lipopolysaccharides. The lipopolysaccharide molecule is important in mediating interactions …

A phosphoethanolamine transferase specific for the outer 3-deoxy-D-manno-octulosonic acid residue of Escherichia coli lipopolysaccharide: Identification of the eptB …

CM Reynolds, SR Kalb, RJ Cotter… - Journal of Biological …, 2005 - ASBMB
Addition of a phosphoethanolamine (pEtN) moiety to the outer 3-deoxy-d-manno-
octulosonic acid (Kdo) residue of lipopolysaccharide (LPS) in WBB06, a heptose-deficient …

The structure of the neisserial lipooligosaccharide phosphoethanolamine transferase A (LptA) required for resistance to polymyxin

C Wanty, A Anandan, S Piek, J Walshe… - Journal of molecular …, 2013 - Elsevier
Gram-negative bacteria possess an outer membrane envelope consisting of an outer leaflet
of lipopolysaccharides, also called endotoxins, which protect the pathogen from …

Phosphoethanolamine Substitution of Lipid A and Resistance of Neisseria gonorrhoeae to Cationic Antimicrobial Peptides and Complement-Mediated Killing by …

LA Lewis, B Choudhury, JT Balthazar… - Infection and …, 2009 - Am Soc Microbiol
The capacity of Neisseria gonorrhoeae to cause disseminated gonococcal infection requires
that such strains resist the bactericidal action of normal human serum. The bactericidal …

Identification of cptA, a PmrA-Regulated Locus Required for Phosphoethanolamine Modification of the Salmonella enterica Serovar Typhimurium …

R Tamayo, B Choudhury, A Septer… - Journal of …, 2005 - Am Soc Microbiol
In response to the in vivo environment, the Salmonella enterica serovar Typhimurium
lipopolysaccharide (LPS) is modified. These modifications are controlled in part by the two …