Focusing on the literature progress since 2002, the present review explores the highly
significant role that multicomponent reactions (MCRs) have played as a very important tool …

Curcumin is the yellow-colored bioactive constituent of the perennial plant, Curcuma longa
L., which possesses a wide range of physiological and pharmacological properties such as …

The three-component condensation reaction of 4-methylbenzaldehyde with acetophenone
and urea in the presence of CF3COOH was investigated and as a result, 4-phenyl-6-(p-tolyl) …

Breast cancer (BC), the most common malignancy in women, results from significant
alterations in genetic and epigenetic mechanisms that alter multiple signaling pathways in …

Several curcumin analogues bearing pyrazole were synthesized and characterized by IR,
NMR, and mass spectral data. There were four tested compounds among 11 synthesized …

With 19.3 million new cases and almost 10 million deaths in 2020, cancer has become a
leading cause of death today. Curcumin and its analogues were found to have promising …

Curcumin is an important phytochemical, found in the Asian countries, especially in the
Indian subcontinent. The use of this “privileged natural product” in the diversity‐oriented …

Cancer is the world's second leading cause of death, accounting for nearly 10 million deaths
and 19.3 million new cases in 2020. Curcumin analogs are gaining popularity as anticancer …

Dihydropyrimidin-2 (1H)-one/thione analogs of curcumin were synthesized in good yield by
a one-pot multi-component cyclocondensation using curcumin, substituted aromatic …

Curcumin is a key constituent of turmeric with a variety of biological activities. From a
chemical point of view, curcumin contains different functional groups that can undergo …