Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

Sepsis, an infection-induced inflammatory syndrome, is a leading and increasing cause of
mortality worldwide. Animal and human observational studies suggest statins may prevent …

Aims Sodium-glucose cotransporter 2 inhibitors have beneficial effects on heart failure and
cardiovascular mortality in diabetic and non-diabetic patients, with unclear mechanisms …

Background and purpose: 5α, 8α‐Epidioxy‐22E‐ergosta‐6, 22‐dien‐3β‐ol (ergosterol
peroxide) is a major antitumour sterol produced by edible or medicinal mushrooms …

Besides cancer prevention, the hypolipidemic effects of tea have been well studied in
animals and humans. Recently, statin has been identified in Pu-erh tea extract. Clinical trials …

During post-natal maturation of the mammalian heart, proliferation of cardiomyocytes
essentially ceases as cardiomyocytes withdraw from the cell cycle and develop blocks at the …

We review fundamental processes, such as mutation, oxidative stress, and inflammation that
are critical for carcinogenesis and provide specific molecular targets for new …

Background: Congestive heart failure (CHF) is a common cause of atrial fibrillation (AF).
Oxidative stress and inflammation (profibrotic) and peroxisome proliferator-activated …

Background/Aim: We have demonstrated that exogenous hydrogen sulfide (H 2 S) protects
H9c2 cardiac cells against the doxorubicin (DOX)-induced injuries by inhibiting p38 mitogen …

Background and Purpose—The pathophysiology of cerebral aneurysms (CAs) is linked to
chronic inflammation and degradation of extracellular matrix in vascular walls. Because …