The silent threat: asymptomatic parasitemia and malaria transmission

KA Lindblade, L Steinhardt, A Samuels… - Expert review of anti …, 2013 - Taylor & Francis
Scale-up of malaria control interventions has resulted in a substantial decline in global
malaria morbidity and mortality. Despite this achievement, there is evidence that current …

Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and elimination

T Bousema, C Drakeley - Clinical microbiology reviews, 2011 - Am Soc Microbiol
Malaria remains a major cause of morbidity and mortality in the tropics, with Plasmodium
falciparum responsible for the majority of the disease burden and P. vivax being the …

Biology of malaria transmission

E Meibalan, M Marti - Cold Spring …, 2017 - perspectivesinmedicine.cshlp.org
Understanding transmission biology at an individual level is a key component of intervention
strategies that target the spread of malaria parasites from human to mosquito. Gametocytes …

The role of submicroscopic parasitemia in malaria transmission: what is the evidence?

JT Lin, DL Saunders, SR Meshnick - Trends in parasitology, 2014 - cell.com
Achieving malaria elimination requires targeting the human reservoir of infection, including
those with asymptomatic infection. Smear-positive asymptomatic infections detectable by …

Molecular evidence for the localization of Plasmodium falciparum immature gametocytes in bone marrow

R Aguilar, A Magallon-Tejada… - Blood, the journal of …, 2014 - ashpublications.org
Plasmodium falciparum immature gametocytes are not observed in peripheral blood.
However, gametocyte stages in organs such as bone marrow have never been assessed by …

Blood-Stage Parasitaemia and Age Determine Plasmodium falciparum and P. vivax Gametocytaemia in Papua New Guinea

C Koepfli, LJ Robinson, P Rarau, M Salib, N Sambale… - PloS one, 2015 - journals.plos.org
A better understanding of human-to-mosquito transmission is crucial to control malaria. In
order to assess factors associated with gametocyte carriage, 2083 samples were collected …

Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta …

WWARN Gametocyte Study Group teun. bousema … - BMC medicine, 2016 - Springer
Background Gametocytes are responsible for transmission of malaria from human to
mosquito. Artemisinin combination therapy (ACT) reduces post-treatment gametocyte …

Plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes

M Usui, SK Prajapati, R Ayanful-Torgby… - Nature …, 2019 - nature.com
Plasmodium sexual differentiation is required for malaria transmission, yet much remains
unknown about its regulation. Here, we quantify early gametocyte-committed ring (gc-ring) …

Trends in malaria prevalence and risk factors associated with the disease in Nkongho-mbeng; a typical rural setting in the equatorial rainforest of the South West …

RB Nyasa, EL Fotabe, RN Ndip - Plos one, 2021 - journals.plos.org
Globally, malaria in recent years has witnessed a decline in the number of cases and death,
though the most recent world malaria report shows a slight decrease in the number of cases …

[HTML][HTML] Biology and epidemiology of Plasmodium falciparum and Plasmodium vivax gametocyte carriage: implication for malaria control and elimination

A Alemayehu - Parasite Epidemiology and Control, 2023 - Elsevier
Malaria is among the leading public health problems worldwide. Female anopheles
mosquito orchestrates the transmission of malaria by taking gametocytes and introducing …