Resolution of inflammation in oral diseases

EG Eltay, T Van Dyke - Pharmacology & therapeutics, 2023 - Elsevier
The resolution of inflammation is an essential endogenous process that protects host tissues
from an exaggerated chronic inflammatory response. Multiple interactions between host …

Proresolving mediators in endodontics: a systematic review

E Cotti, F Ideo, A Pedrazzini, G Bardini, D Musu… - Journal of …, 2021 - Elsevier
Introduction Proresolving lipid mediators are specialized molecules (SPMs) involved in the
active resolution of the inflammatory process by regulating tissue homeostasis. The aim of …

Resolvin E1 accelerates pulp repair by regulating inflammation and stimulating dentin regeneration in dental pulp stem cells

J Chen, H Xu, K Xia, S Cheng, Q Zhang - Stem Cell Research & Therapy, 2021 - Springer
Background Unresolved inflammation and tissue destruction are considered to underlie the
failure of dental pulp repair. As key mediators of the injury response, dental pulp stem cells …

Resolvin D2 induces resolution of periapical inflammation and promotes healing of periapical lesions in rat periapical periodontitis

YD Siddiqui, K Omori, T Ito, K Yamashiro… - Frontiers in …, 2019 - frontiersin.org
Periapical periodontitis results from pulpal infection leading to pulpal necrosis and
resorption of periapical bone. The current treatment is root canal therapy, which attempts to …

Determining the setting of root canal sealers using an in vivo animal experimental model

EJNL Silva, IC Ehrhardt, GC Sampaio… - Clinical Oral …, 2021 - Springer
Objectives To present and explore the potential of an animal-based experimental model
developed to determine the set of root canal sealers in vivo. The setting of AH Plus, BioC …

Final irrigation with bioglass solution in regenerative endodontic procedure induces tissue formation inside the root canals, collagen maturation, proliferation cell and …

KS de Paula, AH dos Reis‐Prado… - International …, 2024 - Wiley Online Library
Aim To evaluate the influence of an experimental solution of cobalt‐doped F18 bioactive
glass (F18Co) on tissue repair following regenerative endodontic procedure (REP) in rat …

Periradicular inflammatory response, bone resorption, and cementum repair after sealing of furcation perforation with mineral trioxide aggregate (MTA Angelus™) or …

M de Sousa Reis, RK Scarparo, L Steier… - Clinical oral …, 2019 - Springer
Objective This study assessed tissue responses after furcation perforation and immediate
sealing with either Biodentine™ or MTA Angelus™. Material and methods Sixty male Wistar …

Influence of ethylenediaminetetraacetic acid irrigation on the regenerative endodontic procedure in an immature rat molar model

AH dos Reis‐Prado, SC Oliveira, J Goto… - International …, 2023 - Wiley Online Library
Aim To analyse the influence of ethylenediaminetetraacetic acid (EDTA) on the repair
process in immature rat molars after a regenerative endodontic procedure (REP) …

Zoledronic acid modulates cytokine expression and mitigates bone loss during the development of induced apical periodontitis in a mice model

CA Maia, HG dos Santos Chaves, F Benetti… - Journal of …, 2023 - Elsevier
Introduction Bisphosphonates are antiresorptive drugs used worldwide to treat systemic
bone pathologies. This study aimed to assess the impact of zoledronic acid on the …

[HTML][HTML] Injectable thermosensitive antibiotic-laden chitosan hydrogel for regenerative endodontics

AH dos Reis-Prado, M Rahimnejad, R Dal-Fabbro… - Bioactive Materials, 2025 - Elsevier
Injectable biomaterials, such as thermosensitive chitosan (CH)-based hydrogels, present a
highly translational potential in dentistry due to their minimally invasive application …