Synthesis of oligonucleotides carrying thiol groups using a simple reagent derived from threoninol

S Pérez-Rentero, S Grijalvo, R Ferreira, R Eritja - Molecules, 2012 - mdpi.com
Oligonucleotides carrying thiol groups are useful intermediates for a remarkable number of
applications involving nucleic acids. In this study, DNA oligonucleotides carrying tert …

Synthesis, Characterization, and Self-Assembly of a Tetrathiafulvalene (TTF)–Triglycyl Derivative

S Pérez-Rentero, R Eritja, M Häring, C Saldías… - Applied Sciences, 2018 - mdpi.com
In this work, we describe the synthesis, characterization, and self-assembly properties of a
new tetrathiafulvalene (TTF)–triglycyl low-molecular-weight (LMW) gelator. Supramolecular …

Biophysical and RNA interference inhibitory properties of oligonucleotides carrying tetrathiafulvalene groups at terminal positions

S Pérez-Rentero, A Somoza, S Grijalvo… - Journal of …, 2013 - Wiley Online Library
Oligonucleotide conjugates carrying a single functionalized tetrathiafulvalene (TTF) unit
linked through a threoninol molecule to the 3′ or 5′ ends were synthesized together with …

Challenges and opportunities for oligonucleotide-based therapeutics by antisense and RNA interference mechanisms

R Eritja, M Terrazas, S Grijalvo, A Aviñó… - Chemical Biology of …, 2014 - Springer
Oligonucleotide-based therapeutics may be one of the most promising approaches for the
treatment of diseases. Although significant progress has been made in developing these …

3 Synthesis of oligonucleotides carrying modified bases for DNA and protein recognition

C Fàbrega, R Eritja - Nucleic Acids Chemistry: Modifications and …, 2021 - degruyter.com
3.1 Hybridization and DNA mutagenesis| 88 3.1. 1 Halogenated nucleobases| 88 3.1. 2 2-
Aminopurine and methoxyamine nucleoside derivatives| 92 3.1. 3 Sulfur-containing …