Role of oxidative stress in male infertility: an updated review

AT Alahmar - Journal of human reproductive sciences, 2019 - journals.lww.com
Current evidence links oxidative stress (OS) to male infertility, reduced sperm motility, sperm
DNA damage and increased risk of recurrent abortions and genetic diseases. A review of …

[HTML][HTML] Recent advances in understanding and managing male infertility

J Fainberg, JA Kashanian - F1000Research, 2019 - ncbi.nlm.nih.gov
Infertility is a prevalent condition affecting an estimated 70 million people globally. The
World Health Organization estimates that 9% of couples worldwide struggle with fertility …

[HTML][HTML] Sperm DNA fragmentation: a new guideline for clinicians

A Agarwal, A Majzoub, S Baskaran… - The world journal of …, 2020 - ncbi.nlm.nih.gov
Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The
spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases …

Impact of advanced paternal age on fertility and risks of genetic disorders in offspring

A Kaltsas, E Moustakli, A Zikopoulos, I Georgiou… - Genes, 2023 - mdpi.com
The average age of fathers at first pregnancy has risen significantly over the last decade
owing to various variables, including a longer life expectancy, more access to contraception …

[HTML][HTML] Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios

A Agarwal, A Majzoub, SC Esteves, E Ko… - Translational …, 2016 - ncbi.nlm.nih.gov
Sperm DNA fragmentation (SDF) has been generally acknowledged as a valuable tool for
male fertility evaluation. While its detrimental implications on sperm function were …

Measuring sperm DNA fragmentation and clinical outcomes of medically assisted reproduction: a systematic review and meta-analysis

M Cissen, M Wely, I Scholten, S Mansell, JP Bruin… - PloS one, 2016 - journals.plos.org
Sperm DNA fragmentation has been associated with reduced fertilization rates, embryo
quality, pregnancy rates and increased miscarriage rates. Various methods exist to test …

Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring

R Sharma, A Agarwal, VK Rohra, M Assidi… - Reproductive Biology …, 2015 - Springer
Over the last decade, there has been a significant increase in average paternal age when
the first child is conceived, either due to increased life expectancy, widespread use of …

Antioxidants for male subfertility

W de Ligny, RM Smits… - Cochrane database …, 2022 - cochranelibrary.com
Background The inability to have children affects 10% to 15% of couples worldwide. A male
factor is estimated to account for up to half of the infertility cases with between 25% to 87% of …

Intracytoplasmic sperm injection for male infertility and consequences for offspring

SC Esteves, M Roque, G Bedoschi, T Haahr… - Nature Reviews …, 2018 - nature.com
Intracytoplasmic sperm injection (ICSI) has become the most commonly used method of
fertilization in assisted reproductive technology. The primary reasons for its popularity stem …

[HTML][HTML] Whether sperm deoxyribonucleic acid fragmentation has an effect on pregnancy and miscarriage after in vitro fertilization/intracytoplasmic sperm injection: a …

J Zhao, Q Zhang, Y Wang, Y Li - Fertility and sterility, 2014 - Elsevier
Objective To examine whether sperm DNA fragmentation has an effect on pregnancy and
miscarriage after IVF and/or intracytoplasmic sperm injection (ICSI). Design Systematic …