Recent advances and next breakthrough in immunotherapy for cancer treatment

L Yang, Q Ning, S Tang - Journal of immunology research, 2022 - Wiley Online Library
With the huge therapeutic potential, cancer immunotherapy is expected to become the
mainstream of cancer treatment. In the current field of cancer immunotherapy, there are …

The development of small-molecule inhibitors targeting HPK1

L Zhou, T Wang, K Zhang, X Zhang, S Jiang - European Journal of …, 2022 - Elsevier
Abstract Hematopoietic progenitor kinase 1 (HPK1), a 97-kDa serine/threonine Ste20-
related protein kinase, is a negative regulator of T cells, B cells, and dendritic cells-mediated …

Electrospun PVP-core/PHBV-shell fibers to eliminate tailing off for an improved sustained release of curcumin

Y Liu, X Chen, DG Yu, H Liu, Y Liu… - Molecular …, 2021 - ACS Publications
Tailing off release in the sustained release of water-insoluble curcumin (Cur) is a significant
challenge in the drug delivery system. As a novel solution, core–shell nanodrug containers …

The nanosystems involved in treating lung cancer

A Crintea, AG Dutu, G Samasca, IA Florian, I Lupan… - Life, 2021 - mdpi.com
Even though there are various types of cancer, this pathology as a whole is considered the
principal cause of death worldwide. Lung cancer is known as a heterogeneous condition …

Engineered photonic near-infrared light activated photothermal theranostic nanovaccine induced targeted remodeling of tumor microenvironment

K Gowsalya, B Rithisa, Y Haldorai, K Shanthi… - … , Biology and Medicine, 2024 - Elsevier
Tumor recurrence, which happens as a result of persisting tumor cells and minor lesions
after treatments like surgery and chemotherapy, is a major problem in oncology. Herein, a …

Cobalt-doped bioactive glasses for biomedical applications: A review

F Baino, M Montazerian, E Verné - Materials, 2023 - mdpi.com
Improving angiogenesis is the key to the success of most regenerative medicine
approaches. However, how and to which extent this may be performed is still a challenge. In …

Exosome-based delivery nanoplatforms: next-generation theranostic platforms for breast cancer

Y Zheng, M Li, B Weng, H Mao, J Zhao - Biomaterials Science, 2022 - pubs.rsc.org
Breast cancer is the most frequent type of malignancy, and the leading cause of cancer-
related death in women across the globe. Exosomes are naturally derived 50–150 nm …

Smart nanotherapeutics and lung cancer

M Doroudian, MH Azhdari, N Goodarzi, D O'Sullivan… - Pharmaceutics, 2021 - mdpi.com
Lung cancer is a significant health problem worldwide. Unfortunately, current therapeutic
strategies lack a sufficient level of specificity and can harm adjacent healthy cells …

Emerging uses of PLA–PEG copolymer in cancer drug delivery

R Mundel, T Thakur, M Chatterjee - 3 Biotech, 2022 - Springer
Traditional therapies need high systematic dosages that not only destroys cancerous cells
but also healthy cells. To overcome this problem recent advancement in nanotechnology …

Synthesis and characterization of bioactive magnetic nanoparticles from the perspective of hyperthermia applications

EA Moacă, V Socoliuc, D Stoian, C Watz, D Flondor… - Magnetochemistry, 2022 - mdpi.com
Magnetic iron oxide nanoparticles were obtained for the first time via the green chemistry
approach, starting from two aqueous extracts of wormwood (Artemisia absinthium L.), both …