New insight into phytochromes: connecting structure to function
Red and far-red light–sensing phytochromes are widespread in nature, occurring in plants,
algae, fungi, and prokaryotes. Despite at least a billion years of evolution, their photosensory …
algae, fungi, and prokaryotes. Despite at least a billion years of evolution, their photosensory …
The red edge: bilin-binding photoreceptors as optogenetic tools and fluorescence reporters
This review adds the bilin-binding phytochromes to the Chemical Reviews thematic issue
“Optogenetics and Photopharmacology”. The work is structured into two parts. We first …
“Optogenetics and Photopharmacology”. The work is structured into two parts. We first …
Protein control of photochemistry and transient intermediates in phytochromes
Phytochromes are ubiquitous photoreceptors responsible for sensing light in plants, fungi
and bacteria. Their photoactivation is initiated by the photoisomerization of the embedded …
and bacteria. Their photoactivation is initiated by the photoisomerization of the embedded …
[HTML][HTML] Optogenetic approaches to study the mammalian brain
Highlights•State-of the art approaches to implement optogenetics in mammals.•Application
principles of optogenetic strategies in freely moving animals.•All-optical approaches …
principles of optogenetic strategies in freely moving animals.•All-optical approaches …
Vibrational couplings between protein and cofactor in bacterial phytochrome Agp1 revealed by 2D-IR spectroscopy
Phytochromes are ubiquitous photoreceptor proteins that undergo a significant refolding of
secondary structure in response to initial photoisomerization of the chromophoric group …
secondary structure in response to initial photoisomerization of the chromophoric group …
Tips and turns of bacteriophytochrome photoactivation
H Takala, P Edlund, JA Ihalainen… - Photochemical & …, 2020 - pubs.rsc.org
Phytochromes are ubiquitous photosensor proteins, which control the growth, reproduction
and movement in plants, fungi and bacteria. Phytochromes switch between two …
and movement in plants, fungi and bacteria. Phytochromes switch between two …
Signal transduction in photoreceptor histidine kinases
A Möglich - Protein science, 2019 - Wiley Online Library
Two‐component systems (TCS) constitute the predominant means by which prokaryotes
read out and adapt to their environment. Canonical TCSs comprise a sensor histidine kinase …
read out and adapt to their environment. Canonical TCSs comprise a sensor histidine kinase …
Photosensing and quorum sensing are integrated to control Pseudomonas aeruginosa collective behaviors
Bacteria convert changes in sensory inputs into alterations in gene expression, behavior,
and lifestyles. A common lifestyle choice that bacteria make is whether to exhibit individual …
and lifestyles. A common lifestyle choice that bacteria make is whether to exhibit individual …
Signaling by a bacterial phytochrome histidine kinase involves a conformational cascade reorganizing the dimeric photoreceptor
ES Burgie, K Basore, MJ Rau, B Summers… - Nature …, 2024 - nature.com
Phytochromes (Phys) are a divergent cohort of bili-proteins that detect light through
reversible interconversion between dark-adapted Pr and photoactivated Pfr states. While our …
reversible interconversion between dark-adapted Pr and photoactivated Pfr states. While our …
A genetically encoded far‐red fluorescent calcium ion biosensor derived from a biliverdin‐binding protein
R Hashizume, H Fujii, S Mehta, K Ota, Y Qian… - Protein …, 2022 - Wiley Online Library
Far‐red and near‐infrared (NIR) genetically encoded calcium ion (Ca2+) indicators (GECIs)
are powerful tools for in vivo and multiplexed imaging of neural activity and cell signaling …
are powerful tools for in vivo and multiplexed imaging of neural activity and cell signaling …