Biochemistry textbooks and cell culture experiments seem to be telling us two different
things about the significance of external glutamine supply for mammalian cell growth and …

T cell acute lymphoblastic leukaemia (T-ALL) is an aggressive haematological malignancy
derived from early T cell progenitors. In recent years genomic and transcriptomic studies …

DNA methylation patterns are disrupted in various malignancies, suggesting a role in the
development of cancer, but genetic aberrations directly linking the DNA methylation …

Early T-cell precursor (ETP) acute lymphoblastic leukemia/lymphoma (ALL/LBL) is a recently
recognized high-risk T lymphoblastic leukemia/lymphoma (T-ALL/LBL) subgroup. The …

Cells acquire their ultimate identities by activating combinations of transcription factors that
initiate and sustain expression of the appropriate cell type-specific genes. T cell …

Early T-cell precursor (ETP) acute lymphoblastic leukemia (ALL) is a recently described
subtype of T-ALL characterized by a unique immunophenotype and genomic profile, as well …

T-cell acute lymphoblastic leukemia (T-ALL) is a high-risk subtype of acute lymphoblastic
leukemia (ALL) with gradually improved survival through introduction of intensified …

T-cell immunophenotype of acute lymphoblastic leukemia (T-ALL) is an uncommon
aggressive leukemia that can present with leukemic and/or lymphomatous manifestations …

DNA methylation is an epigenetic process involved in development, aging, and cancer.
Although the advent of new molecular techniques has enhanced our knowledge of how …

We investigated the outcome for children and young people with Early T‐precursor acute
lymphoblastic leukaemia (ETP‐ALL), a recently described poor prognosis sub‐group of T …