Parkinson's disease: A review

DM Radhakrishnan, V Goyal - Neurology India, 2018 - journals.lww.com
Parkinson's disease is a common movement disorder seen in neurological practice, but the
diagnosis and management is challenging. The diagnosis is clinical and sometimes difficult …

Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update

K Nuytemans, J Theuns, M Cruts… - Human …, 2010 - Wiley Online Library
To date, molecular genetic analyses have identified over 500 distinct DNA variants in five
disease genes associated with familial Parkinson disease; α‐synuclein (SNCA), parkin …

[HTML][HTML] Anxiety: An ignored aspect of Parkinson's disease lacking attention

DK Khatri, M Choudhary, A Sood, SB Singh - Biomedicine & …, 2020 - Elsevier
Parkinson's disease (PD) is a progressive neurodegenerative disease which affects millions
of population worldwide. It is characterized by motor symptoms such as excessive tremor …

Acetylation, phosphorylation, ubiquitination (oh my!): Following post-translational modifications on the ubiquitin road

RE Lacoursiere, D Hadi, GS Shaw - Biomolecules, 2022 - mdpi.com
Ubiquitination is controlled by a series of E1, E2, and E3 enzymes that can ligate ubiquitin to
cellular proteins and dictate the turnover of a substrate and the outcome of signalling events …

Pleiotropic effects for Parkin and LRRK2 in leprosy type-1 reactions and Parkinson's disease

VM Fava, YZ Xu, G Lettre, N Van Thuc… - Proceedings of the …, 2019 - National Acad Sciences
Type-1 reactions (T1R) are pathological inflammatory episodes and main contributors to
nerve damage in leprosy. Here, we evaluate the genewise enrichment of rare protein …

Research in Parkinson's disease in India: A review

P Surathi, K Jhunjhunwala, R Yadav… - Annals of Indian …, 2016 - journals.lww.com
Parkinson's disease (PD) is a common neurodegenerative disorder affecting patients in
large numbers throughout the world. In this article, we review all the published data on PD …

Epidemiology of Parkinson disease in the city of Kolkata, India: a community-based study

SK Das, AK Misra, BK Ray, A Hazra, MK Ghosal… - Neurology, 2010 - AAN Enterprises
Objective: No well-designed longitudinal study on Parkinson disease (PD) has been
conducted in India. Therefore, we planned to determine the prevalence, incidence, and …

Genomic and pharmacogenomic biomarkers of Parkinson's disease

H Alonso-Navarro… - Current drug …, 2014 - ingentaconnect.com
The relative role of genetic and environmental factors in the pathogenesis of Parkinson's
disease (PD) has been the matter of investigation and debate, especially in the last 30 …

Environmental and familial risk factors of Parkinsons disease: case-control study

J Sanyal, DP Chakraborty, B Sarkar… - Canadian journal of …, 2010 - cambridge.org
Background: While the cause of Parkinson's disease (PD) remains unknown, evidence
suggests certain environmental factors, such as well water drinking, herbicides, pesticides …

The Landscape of Monogenic Parkinson's Disease in Populations of Non-European Ancestry: A Narrative Review

C Koros, A Bougea, AM Simitsi, N Papagiannakis… - Genes, 2023 - mdpi.com
Introduction: There has been a bias in the existing literature on Parkinson's disease (PD)
genetics as most studies involved patients of European ancestry, mostly in Europe and …