Recent advances in aptamer discovery and applications

Y Zhang, BS Lai, M Juhas - Molecules, 2019 - mdpi.com
Aptamers are short, single-stranded DNA, RNA, or synthetic XNA molecules that can be
developed with high affinity and specificity to interact with any desired targets. They have …

Application of aptamers in virus detection and antiviral therapy

X Zou, J Wu, J Gu, L Shen, L Mao - Frontiers in microbiology, 2019 - frontiersin.org
Viral infections can cause serious diseases for humans and animals. Accurate and early
detection of viruses is often crucial for clinical diagnosis and therapy. Aptamers are mostly …

Aptamers from cell-based selection for bioanalytical applications

W Tan, MJ Donovan, J Jiang - Chemical reviews, 2013 - ACS Publications
Nucleic acids are the foundation of life. Specific sequences translate certain genetic traits,
protein expression, and, ultimately, cellular function. Yet, nucleic acids not only store genetic …

Aptamer in bioanalytical applications

AB Iliuk, L Hu, WA Tao - Analytical chemistry, 2011 - ACS Publications
(2009À2010), thefield of aptamer research has continuously generated lots of interest in the
scientific community. Aptamers, first reported by three groups independently in 1990, 1À3 …

Aptamers against pathogenic bacteria: selection strategies and apta-assay/aptasensor application for food safety

M Liu, F Yue, Q Kong, Z Liu, Y Guo… - Journal of Agricultural …, 2022 - ACS Publications
Pathogenic bacteria are primarily kinds of detrimental agents that cause mankind illness via
contaminated food with traits of multiple types, universality, and low content. In view of the …

Detecting biothreat agents: From current diagnostics to developing sensor technologies

SA Walper, G Lasarte Aragonés, KE Sapsford… - ACS …, 2018 - ACS Publications
Although a fundamental understanding of the pathogenicity of most biothreat agents has
been elucidated and available treatments have increased substantially over the past …

Nucleic acid aptamer-based methods for diagnosis of infections

KS Park - Biosensors and Bioelectronics, 2018 - Elsevier
Infectious diseases are a serious global problem, which not only take an enormous human
toll but also incur tremendous economic losses. In combating infectious diseases, rapid and …

Selection of HBsAg-specific DNA aptamers based on carboxylated magnetic nanoparticles and their application in the rapid and simple detection of hepatitis B virus …

Z Xi, R Huang, Z Li, N He, T Wang, E Su… - ACS Applied Materials …, 2015 - ACS Publications
Aptamers are short single-stranded DNA or RNA oligonucleotides and can be selected from
synthetic combinatorial libraries in vitro. They have a high binding affinity and specificity for …

ABCs of DNA aptamer and related assay development

TK Sharma, JG Bruno, A Dhiman - Biotechnology advances, 2017 - Elsevier
This review is intended to guide the novice in aptamer research and development to
understand virtually all of the aptamer development options and currently available assay …

Whole-bacterium SELEX of DNA aptamers for rapid detection of E. coli O157: H7 using a QCM sensor

X Yu, F Chen, R Wang, Y Li - Journal of biotechnology, 2018 - Elsevier
The rapid detection of foodborne pathogens is critical to ensure food safety. The objective of
this study is to select aptamers specifically bound to Escherichia coli O157: H7 using the …