A large population of neural stem/precursor cells (NSCs) persists in the ventricular–
subventricular zone (V-SVZ) located in the walls of the lateral brain ventricles. V-SVZ NSCs …

The sophisticated circuitry of the neocortex is assembled from a diverse repertoire of
neuronal subtypes generated during development under precise molecular regulation. In …

Adult neural stem/progenitor (B1) cells within the walls of the lateral ventricles generate
different types of neurons for the olfactory bulb (OB). The location of B1 cells determines the …

Neural stem cells (NSCs) in the adult mammalian brain serve as a reservoir for the
generation of new neurons, oligodendrocytes, and astrocytes. Here, we use single-cell RNA …

Glial cells were long considered end products of neural differentiation, specialized
supportive cells with an origin very different from that of neurons. New studies have shown …

DNA methylation at proximal promoters facilitates lineage restriction by silencing cell type–
specific genes. However, euchromatic DNA methylation frequently occurs in regions outside …

The in vivo potential of neural stem cells in the postnatal mouse brain is not known, but
because they produce many different types of neurons, they must be either very versatile or …

Cortical GABAergic inhibitory interneurons have crucial roles in the development and
function of the cerebral cortex. In rodents, nearly all neocortical interneurons are generated …

The mammalian telencephalon is considered the most complex of all biological structures. It
comprises a large number of functionally and morphologically distinct types of neurons that …

Throughout life, neural stem cells (NSCs) in different domains of the ventricular-
subventricular zone (V-SVZ) of the adult rodent brain generate several subtypes of …