The demonstration of the existence of non-covalent bonding interactions between different
biomolecules (DNA, enzymes, proteins) and drugs or potentially mutagenic agents requires …

Nonequilibrium capillary electrophoresis of equilibrium mixtures (NECEEM) is a versatile
tool for studying affinity binding. Here we describe a NECEEM-based approach for …

We report direct quantitative analysis of multiple miRNAs with a detection limit of 1000
copies without miRNA enrichment or modification. A 300-fold improvement over the …

The bioactivities and bioavailability of plant polyphenols including proanthocyanidins and
other catechin derivatives may be affected by covalent reaction between polyphenol and …

Capillary electrophoresis (CE) serves as a platform for a large family of temperature-
sensitive affinity methods. To control the electrolyte temperature, the heat generated during …

Direct quantitative analysis of multiple miRNAs (DQAMmiR) is a hybridization-based assay,
in which the excess of the DNA hybridization probes is separated from the miRNA-probe …

Cladophora members are present in seawater and freshwater ecosystems worldwide. Their
growth poses a serious threat to water environment, fisheries, production and living. In order …

To better understand the regulatory roles of miRNA in biological functions and to use miRNA
as molecular markers of diseases, we need to accurately measure amounts of multiple …

MicroRNA (miRNA) are short single-stranded RNA molecules that function as post-
transcriptional regulators in gene expression, The abnormal expression of small subsets of …

The inherent separation inefficiencies of the excess probes and hybrids and the hybrids from
each other limits the use of capillary electrophoresis (CE) for hybridization-based analysis of …