Staphylococcus aureus pathogenesis in diverse host environments

D Balasubramanian, L Harper, B Shopsin… - Pathogens and …, 2017 - academic.oup.com
Staphylococcus aureus is an eminent human pathogen that can colonize the human host
and cause severe life-threatening illnesses. This bacterium can reside in and infect a wide …

Function and regulation of Staphylococcus aureus wall teichoic acids and capsular polysaccharides

D Keinhoerster, SE George, C Weidenmaier… - International Journal of …, 2019 - Elsevier
Staphylococcus aureus produces different secondary cell wall glycopolymers such as wall
teichoic acids (WTA) and capsular polysaccharides (CP). These structures play an important …

Wall teichoic acids mediate increased virulence in Staphylococcus aureus

S Wanner, J Schade, D Keinhörster, N Weller… - Nature …, 2017 - nature.com
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) are the
cause of a severe pandemic consisting primarily of skin and soft tissue infections. The …

SarS is a repressor of Staphylococcus aureus bicomponent pore-forming leukocidins

EE Anderson, S Dyzenhaus, JK Ilmain… - Infection and …, 2023 - Am Soc Microbiol
Staphylococcus aureus is a successful pathogen that produces a wide range of virulence
factors that it uses to subvert and suppress the immune system. These include the …

Staphylococcus aureus arsenal to conquer the lower respiratory tract

M Pivard, K Moreau, F Vandenesch - Msphere, 2021 - Am Soc Microbiol
Staphylococcus aureus is both a commensal and a pathogenic bacterium for humans. Its
ability to induce severe infections is based on a wide range of virulence factors. S. aureus …

Staphylococcus aureus coordinates leukocidin expression and pathogenesis by sensing metabolic fluxes via RpiRc

D Balasubramanian, EA Ohneck, J Chapman, A Weiss… - MBio, 2016 - Am Soc Microbiol
Staphylococcus aureus is a formidable human pathogen that uses secreted cytolytic factors
to injure immune cells and promote infection of its host. Of these proteins, the bicomponent …

High Production of LukMF' in Staphylococcus aureus Field Strains Is Associated with Clinical Bovine Mastitis

J Hoekstra, V Rutten, L Sommeling, T Van Werven… - Toxins, 2018 - mdpi.com
Staphylococcus aureus, a major cause of bovine mastitis, produces a wide range of immune-
evasion molecules. The bi-component leukocidin LukMF'is a potent killer of bovine …

The major autolysin atl regulates the virulence of staphylococcus aureus by controlling the sorting of lukAB

X Zheng, SX Ma, A St. John, VJ Torres - Infection and Immunity, 2022 - Am Soc Microbiol
Infections caused by the Gram-positive bacterium Staphylococcus aureus remain a
significant health threat globally. The production of bicomponent pore-forming leukocidins …

Bacterial Anti-adhesives: Inhibition of Staphylococcus aureus Nasal Colonization

AC Leonard, LE Petrie, G Cox - ACS Infectious Diseases, 2019 - ACS Publications
Bacterial adhesion to the skin and mucosa is often a fundamental and early step in host
colonization, the establishment of bacterial infections, and pathology. This process is …

Multi-targeted metallo-ciprofloxacin derivatives rationally designed and developed to overcome antimicrobial resistance

Z Ude, N Flothkötter, G Sheehan, M Brennan… - International Journal of …, 2021 - Elsevier
Antimicrobial resistance is a major global threat to human health due to the rise, spread and
persistence of multi-drug-resistant bacteria or 'superbugs'. There is an urgent need to …