Advances and challenges in metatranscriptomic analysis

M Shakya, CC Lo, PSG Chain - Frontiers in genetics, 2019 - frontiersin.org
Sequencing-based analyses of microbiomes have traditionally focused on addressing the
question of community membership and profiling taxonomic abundance through amplicon …

[HTML][HTML] A review of computational tools for generating metagenome-assembled genomes from metagenomic sequencing data

C Yang, D Chowdhury, Z Zhang, WK Cheung… - Computational and …, 2021 - Elsevier
Metagenomic sequencing provides a culture-independent avenue to investigate the
complex microbial communities by constructing metagenome-assembled genomes (MAGs) …

Multi-omics data integration considerations and study design for biological systems and disease

S Graw, K Chappell, CL Washam, A Gies, J Bird… - Molecular omics, 2021 - pubs.rsc.org
With the advancement of next-generation sequencing and mass spectrometry, there is a
growing need for the ability to merge biological features in order to study a system as a …

Dissolved storage glycans shaped the community composition of abundant bacterioplankton clades during a North Sea spring phytoplankton bloom

C Sidhu, IV Kirstein, CL Meunier, J Rick, V Fofonova… - Microbiome, 2023 - Springer
Background Blooms of marine microalgae play a pivotal role in global carbon cycling. Such
blooms entail successive blooms of specialized clades of planktonic bacteria that …

Metagenomic data assembly–the way of decoding unknown microorganisms

AL Lapidus, AI Korobeynikov - Frontiers in Microbiology, 2021 - frontiersin.org
Metagenomics is a segment of conventional microbial genomics dedicated to the
sequencing and analysis of combined genomic DNA of entire environmental samples. The …

Multi-omics reveal microbial determinants impacting the treatment outcome of antidepressants in major depressive disorder

Y Wang, J Zhou, J Ye, Z Sun, Y He, Y Zhao, S Ren… - Microbiome, 2023 - Springer
Background There is a growing body of evidence suggesting that disturbance of the gut-
brain axis may be one of the potential causes of major depressive disorder (MDD). However …

Tapping the role of microbial biosurfactants in pesticide remediation: an eco-friendly approach for environmental sustainability

A Raj, A Kumar, JF Dames - Frontiers in Microbiology, 2021 - frontiersin.org
Pesticides are used indiscriminately all over the world to protect crops from pests and
pathogens. If they are used in excess, they contaminate the soil and water bodies and …

Metabolic framework of spontaneous and synthetic sourdough metacommunities to reveal microbial players responsible for resilience and performance

FM Calabrese, H Ameur, O Nikoloudaki, G Celano… - Microbiome, 2022 - Springer
Background In nature, microbial communities undergo changes in composition that threaten
their resiliency. Here, we interrogated sourdough, a natural cereal-fermenting …

Particle-attached bacteria act as gatekeepers in the decomposition of complex phytoplankton polysaccharides

FQ Wang, D Bartosik, C Sidhu, R Siebers, DC Lu… - Microbiome, 2024 - Springer
Background Marine microalgae (phytoplankton) mediate almost half of the worldwide
photosynthetic carbon dioxide fixation and therefore play a pivotal role in global carbon …

metaGEM: reconstruction of genome scale metabolic models directly from metagenomes

F Zorrilla, F Buric, KR Patil… - Nucleic Acids Research, 2021 - academic.oup.com
Metagenomic analyses of microbial communities have revealed a large degree of
interspecies and intraspecies genetic diversity through the reconstruction of metagenome …