Since the discovery of vitamin C, the number of its known biological functions is continually
expanding. Both the names ascorbic acid and vitamin C reflect its antiscorbutic properties …

Brain cancer is regarded among the deadliest forms of cancer worldwide. The distinct tumor
microenvironment and inherent characteristics of brain tumor cells virtually render them …

Ascorbate (AscH−) functions as a versatile reducing agent. At pharmacological doses (P-
AscH−;[plasma AscH−]≥≈ 20 mM), achievable through intravenous delivery, oxidation of P …

Ascorbate (vitamin C) was an early, unorthodox therapy for cancer, with an outstanding
safety profile and anecdotal clinical benefit. Because oral ascorbate was ineffective in two …

Whether vitamin C (ascorbate) has a role to play as an anti-cancer agent has been debated
for decades. Ascorbate has been used by cancer patients in an unregulated environment …

The use of intravenous vitamin C (IVC) for cancer therapy has long been an area of intense
controversy. Despite this, high dose IVC has been administered for decades by …

Vitamin C (ascorbic acid) is a water-soluble antioxidant and a cofactor for a large number of
enzymes. It is present in all tissues and especially abundant in corneal epithelium, stem …

Nutritional supplements are widely used among patients with cancer who perceive them to
be anticancer and antitoxicity agents. Depending on the type of malignancy and the gender …

Glioblastoma multiforme (GBM) is a highly aggressive neoplasia, prognosis remains dismal,
and current therapy is mostly palliative. There are no known risk factors associated with …

Vitamin C (L-ascorbic acid, ascorbate, VC) is a potential chemotherapeutic agent for cancer
patients. However, the anti-tumor effects of pharmacologic VC on hepatocellular carcinoma …