Asthma remission: what is it and how can it be achieved?

D Thomas, VM McDonald, ID Pavord… - European Respiratory …, 2022 - Eur Respiratory Soc
Asthma treatment goals currently focus on symptom and exacerbation control rather than
remission. Remission is not identical to cure, but is a step closer. This review considers the …

[HTML][HTML] Severe Asthma Network Italy definition of clinical remission in severe asthma: a Delphi consensus

GW Canonica, F Blasi, GE Carpagnano… - The Journal of Allergy …, 2023 - Elsevier
Severe asthma affects about 10% of the population with asthma and is characterized by low
lung function and a high count of blood leukocytes, mainly eosinophils. Various definitions …

Drug nanodelivery systems based on natural polysaccharides against different diseases

A Rehman, SM Jafari, Q Tong, T Riaz… - Advances in Colloid and …, 2020 - Elsevier
Drug nanodelivery systems (DNDSs) are fascinated cargos to achieve outstanding
therapeutic results of various drugs or natural bioactive compounds owing to their unique …

Fucoxanthin ameliorates oxidative stress and airway inflammation in tracheal epithelial cells and asthmatic mice

SJ Wu, CJ Liou, YL Chen, SC Cheng, WC Huang - Cells, 2021 - mdpi.com
Fucoxanthin is isolated from brown algae and was previously reported to have multiple
pharmacological effects, including anti-tumor and anti-obesity effects in mice. Fucoxanthin …

Dupilumab induces long-term on-treatment clinical remission in patients with type 2 asthma

ID Pavord, KF Rabe, E Israel, SJ Szefler… - The Journal of Allergy …, 2024 - Elsevier
Background Remission is proposed as a multicomponent outcome for patients with severe
asthma. Objective This post hoc analysis of QUEST (NCT02414854) and TRAVERSE …

Defining response to therapy with biologics in severe asthma: from global evaluation to super response and remission

AI Papaioannou, E Fouka, K Bartziokas… - Expert Review of …, 2023 - Taylor & Francis
Introduction In recent years, monoclonal antibodies targeting Type-2 inflammatory pathways
have been developed for severe asthma treatment. However, even when patients are …

SANI clinical remission definition: a useful tool in severe asthma management

GW Canonica, D Bagnasco, B Bondi, G Varricchi… - Journal of …, 2024 - Taylor & Francis
In the field of severe asthma, the concept of disease control has recently been integrated by
the one of clinical remission. With this new concept, we move on to analyze the efficacy of …

Immunologic aspects of asthma: from molecular mechanisms to disease pathophysiology and clinical translation

C Xie, J Yang, A Gul, Y Li, R Zhang, M Yalikun… - Frontiers in …, 2024 - frontiersin.org
In the present review, we focused on recent translational and clinical discoveries in asthma
immunology, facilitating phenotyping and stratified or personalized interventions for patients …

[HTML][HTML] Identifying super-responders: a review of the road to asthma remission

S Mailhot-Larouche, C Celis-Preciado… - Annals of Allergy …, 2024 - Elsevier
Asthma is a chronic respiratory disease marked by heterogeneity and variable clinical
outcomes. Recent therapeutic advances have highlighted patients achieving optimal …

Interleukin 4 gene polymorphism (−589C/T) and the risk of asthma: a meta-analysis and met-regression based on 55 studies

A Kousha, A Mahdavi Gorabi, M Forouzesh… - BMC immunology, 2020 - Springer
Background Numerous investigations have previously evaluated the association of
interleukin (IL) 4 gene polymorphisms and the risk of asthma, conferring inconsistent results …