Despite considerable progress in treating cardiac disorders, the prevalence of heart failure
(HF) keeps growing, making it a global medical and economic burden. HF is characterized …

Introduction Recent advances in human cardiac 3D approaches have yielded progressively
more complex and physiologically relevant culture systems. However, their application in the …

The prevalence of heart failure (HF), including reduced ejection fraction (HFrEF) and
preserved ejection fraction (HFpEF), has increased significantly worldwide. However, the …

In response to heart injury, inflammation, or mechanical overload, quiescent cardiac
fibroblasts (CFs) can become activated myofibroblasts leading to pathological matrix …

This paper proposes an innovative approach to generate a generalized myocardial
ischemia database by modeling the virtual electrophysiology of the heart and the 12-lead …

Remodeling in atrial fibrillation (AF) underlines the electrical and structural changes in the
atria, where fibrosis is a hallmark of arrhythmogenic structural alterations. Fibrosis is an …

Background Human cardiac organoids closely replicate the architecture and function of the
human heart, offering a potential accurate platform for studying cellular and molecular …

В обзоре представлены данные о причинах дисрегуляции метаболизма кальция и его
ассоциации с основными элементами сердечно-сосудистого континуума. Особое …

Connexin 43 (CX43) is one of the major components of gap junctions, the structures
responsible for the intercellular communication and transmission of the electrical impulse in …

Heart failure (HF), the leading cause of death among men and women world-wide, causes
great health and economic burdens. HF can be triggered by many factors, such as coronary …