Molecular and neuronal substrates for general anaesthetics

U Rudolph, B Antkowiak - Nature Reviews Neuroscience, 2004 - nature.com
Although general anaesthesia has been of tremendous importance for the development of
surgery, the underlying mechanisms by which this state is achieved are only just beginning …

A narrative review on clinical applications of fNIRS

MA Rahman, AB Siddik, TK Ghosh, F Khanam… - Journal of Digital …, 2020 - Springer
Functional near-infrared spectroscopy (fNIRS) is a relatively new imaging modality in the
functional neuroimaging research arena. The fNIRS modality non-invasively investigates the …

The fMRI signal, slow cortical potential and consciousness

BJ He, ME Raichle - Trends in cognitive sciences, 2009 - cell.com
As functional magnetic resonance imaging (fMRI) has become a driving force in cognitive
neuroscience, it is crucial to understand the neural basis of the fMRI signal. Here, we …

Neural systems for speech and song in autism

G Lai, SP Pantazatos, H Schneider, J Hirsch - Brain, 2012 - academic.oup.com
Despite language disabilities in autism, music abilities are frequently preserved.
Paradoxically, brain regions associated with these functions typically overlap, enabling …

Dissociating speech perception and comprehension at reduced levels of awareness

MH Davis, MR Coleman, AR Absalom… - Proceedings of the …, 2007 - National Acad Sciences
We used functional MRI and the anesthetic agent propofol to assess the relationship among
neural responses to speech, successful comprehension, and conscious awareness …

Functional connectivity and alterations in baseline brain state in humans

R Martuzzi, R Ramani, M Qiu, N Rajeevan… - Neuroimage, 2010 - Elsevier
This work examines the influence of changes in baseline activity on the intrinsic functional
connectivity fMRI (fc-fMRI) in humans. Baseline brain activity was altered by inducing …

The role of fMRI in drug discovery

RG Wise, I Tracey - … Resonance Imaging: An Official Journal of …, 2006 - Wiley Online Library
Pharmacological functional (phMRI) studies are making a significant contribution to our
understanding of drug‐effects on brain systems. Pharmacological fMRI has an additional …

Disconnecting consciousness: is there a common anesthetic end point?

AG Hudetz, GA Mashour - Anesthesia & Analgesia, 2016 - journals.lww.com
In this article, we review (1) the importance of information integration in consciousness,(2)
early studies of network breakdown during anesthesia,(3) preclinical research …

Baseline brain energy supports the state of consciousness

RG Shulman, F Hyder… - Proceedings of the …, 2009 - National Acad Sciences
An individual, human or animal, is defined to be in a conscious state empirically by the
behavioral ability to respond meaningfully to stimuli, whereas the loss of consciousness is …

Propofol disrupts functional interactions between sensory and high‐order processing of auditory verbal memory

X Liu, KK Lauer, BD Ward, SM Rao, SJ Li… - Human brain …, 2012 - Wiley Online Library
Current theories suggest that disrupting cortical information integration may account for the
mechanism of general anesthesia in suppressing consciousness. Human cognitive …