Designing degradable hydrogels for orthogonal control of cell microenvironments

PM Kharkar, KL Kiick, AM Kloxin - Chemical Society Reviews, 2013 - pubs.rsc.org
Degradable and cell-compatible hydrogels can be designed to mimic the physical and
biochemical characteristics of native extracellular matrices and provide tunability of …

Natural photoreceptors as a source of fluorescent proteins, biosensors, and optogenetic tools

DM Shcherbakova, AA Shemetov… - Annual review of …, 2015 - annualreviews.org
Genetically encoded optical tools have revolutionized modern biology by allowing detection
and control of biological processes with exceptional spatiotemporal precision and sensitivity …

Middle-out methods for spatiotemporal tissue engineering of organoids

MR Blatchley, KS Anseth - Nature Reviews Bioengineering, 2023 - nature.com
Organoids recapitulate many aspects of the complex three-dimensional (3D) organization
found within native tissues and even display tissue and organ-level functionality. Traditional …

[HTML][HTML] 3D photo-fabrication for tissue engineering and drug delivery

RF Pereira, PJ Bártolo - Engineering, 2015 - Elsevier
The most promising strategies in tissue engineering involve the integration of a triad of
biomaterials, living cells, and biologically active molecules to engineer synthetic …

Stereolithographic printing of ionically-crosslinked alginate hydrogels for degradable biomaterials and microfluidics

TM Valentin, SE Leggett, PY Chen, JK Sodhi… - Lab on a Chip, 2017 - pubs.rsc.org
3D printed biomaterials with spatial and temporal functionality could enable interfacial
manipulation of fluid flows and motile cells. However, such dynamic biomaterials are …

Polymeric biomaterials with engineered degradation

S Deshayes, AM Kasko - Journal of Polymer Science Part A …, 2013 - Wiley Online Library
Polymeric biomaterials are widely used as carriers for cells and therapeutic agents. Until
recently, most research has been limited to a relatively narrow number of monomers and …

Ratchetaxis: long-range directed cell migration by local cues

D Caballero, J Comelles, M Piel, R Voituriez… - Trends in cell …, 2015 - cell.com
Directed cell migration is usually thought to depend on the presence of long-range gradients
of either chemoattractants or physical properties such as stiffness or adhesion. However, in …

Optogenetic tools for mammalian systems

K Müller, W Weber - Molecular BioSystems, 2013 - pubs.rsc.org
Light is fundamental to life on earth. Therefore, nature has evolved a multitude of
photoreceptors that sense light across all kingdoms. This natural resource provides synthetic …

Dual photosensitive polymers with wavelength‐selective photoresponse

L García‐Fernández, C Herbivo, VSM Arranz… - Advanced …, 2014 - Wiley Online Library
DOI: 10.1002/adma. 201401290 different families of PRPGs, sequential activation of
individual protected reactive groups in a mixture has been realized using light of different …

Cell migration on planar and three-dimensional matrices: a hydrogel-based perspective

LT Vu, G Jain, BD Veres… - Tissue Engineering Part B …, 2015 - liebertpub.com
The migration of cells is a complex process that is dependent on the properties of the
surrounding environment. In vivo, the extracellular environment is complex with a wide …