Assessing the infectious reservoir of falciparum malaria: past and future
Renewed interest in malaria eradication has placed greater emphasis on the development
of tools to interrupt Plasmodium transmission, such as transmission-blocking vaccines …
of tools to interrupt Plasmodium transmission, such as transmission-blocking vaccines …
Genotyping cognate Plasmodium falciparum in humans and mosquitoes to estimate onward transmission of asymptomatic infections
Malaria control may be enhanced by targeting reservoirs of Plasmodium falciparum
transmission. One putative reservoir is asymptomatic malaria infections and the scale of their …
transmission. One putative reservoir is asymptomatic malaria infections and the scale of their …
The relevance and applicability of oocyst prevalence as a read-out for mosquito feeding assays
WJR Stone, M Eldering, GJ van Gemert, KHW Lanke… - Scientific reports, 2013 - nature.com
Mosquito feeding assays are important in evaluations of malaria transmission-reducing
interventions. The proportion of mosquitoes with midgut oocysts is commonly used as an …
interventions. The proportion of mosquitoes with midgut oocysts is commonly used as an …
Variation in natural exposure to anopheles mosquitoes and its effects on malaria transmission
WM Guelbeogo, BP Gonçalves, L Grignard, J Bradley… - Elife, 2018 - elifesciences.org
Variation in biting frequency by Anopheles mosquitoes can explain some of the
heterogeneity in malaria transmission in endemic areas. In this study in Burkina Faso, we …
heterogeneity in malaria transmission in endemic areas. In this study in Burkina Faso, we …
Two-faced immunity? The evidence for antibody enhancement of malaria transmission
Plasmodium gametocytes can induce an immune response in humans that interferes with
the development of sexual-stage parasites in the mosquito gut. Many early studies of the …
the development of sexual-stage parasites in the mosquito gut. Many early studies of the …
R H: a genetic metric for measuring intrahost Plasmodium falciparum relatedness and distinguishing cotransmission from superinfection
Multiple-strain (polygenomic) infections are a ubiquitous feature of Plasmodium falciparum
parasite population genetics. Under simple assumptions of superinfection, polygenomic …
parasite population genetics. Under simple assumptions of superinfection, polygenomic …
The Anopheles gambiae 2La chromosome inversion is associated with susceptibility to Plasmodium falciparum in Africa
Chromosome inversions suppress genetic recombination and establish co-adapted gene
complexes, or supergenes. The 2La inversion is a widespread polymorphism in the …
complexes, or supergenes. The 2La inversion is a widespread polymorphism in the …
Effects of the kdr resistance mutation on the susceptibility of wild Anopheles gambiae populations to Plasmodium falciparum: a hindrance for vector control
MO Ndiath, A Cailleau, SM Diedhiou, A Gaye… - Malaria journal, 2014 - Springer
Background In the context of generalization of insecticide resistance, the hypothesis that
insecticide resistance has a positive impact on the capacity of mosquitoes to transmit …
insecticide resistance has a positive impact on the capacity of mosquitoes to transmit …
Modeling the genetic relatedness of Plasmodium falciparum parasites following meiotic recombination and cotransmission
Unlike in most pathogens, multiple-strain (polygenomic) infections of P. falciparum are
frequently composed of genetic siblings. These genetic siblings are the result of sexual …
frequently composed of genetic siblings. These genetic siblings are the result of sexual …
Reticulate Speciation and Barriers to Introgression in the Anopheles gambiae Species Complex
JE Crawford, MM Riehle, WM Guelbeogo… - Genome Biology and …, 2015 - academic.oup.com
Speciation as a process remains a central focus of evolutionary biology, but our
understanding of the genomic architecture and prevalence of speciation in the face of gene …
understanding of the genomic architecture and prevalence of speciation in the face of gene …