Molecular mechanisms and emerging therapeutics for osteoporosis

JY Noh, Y Yang, H Jung - International journal of molecular sciences, 2020 - mdpi.com
Osteoporosis is the most common chronic metabolic bone disease. It has been estimated
that more than 10 million people in the United States and 200 million men and women …

[HTML][HTML] Osteoporosis: Pathophysiology and therapeutic options

U Föger-Samwald, P Dovjak, U Azizi-Semrad… - EXCLI …, 2020 - ncbi.nlm.nih.gov
Osteoporosis is a metabolic bone disease that, on a cellular level, results from osteoclastic
bone resorption not compensated by osteoblastic bone formation. This causes bones to …

New progress in the pharmacology of protocatechuic acid: A compound ingested in daily foods and herbs frequently and heavily

J Song, Y He, C Luo, B Feng, F Ran, H Xu, Z Ci… - Pharmacological …, 2020 - Elsevier
Protocatechuic acid is a natural phenolic acid, which widely exists in our daily diet and
herbs. It is also one of the main metabolites of complex polyphenols, such as anthocyanins …

Osteoclast multinucleation: review of current literature

J Kodama, T Kaito - International journal of molecular sciences, 2020 - mdpi.com
Multinucleation is a hallmark of osteoclast maturation. The unique and dynamic
multinucleation process not only increases cell size but causes functional alterations …

The development of molecular biology of osteoporosis

Y Gao, S Patil, J Jia - International journal of molecular sciences, 2021 - mdpi.com
Osteoporosis is one of the major bone disorders that affects both women and men, and
causes bone deterioration and bone strength. Bone remodeling maintains bone mass and …

Osteoporosis therapies and their mechanisms of action

B Kim, YJ Cho, W Lim - Experimental and therapeutic …, 2021 - spandidos-publications.com
Osteoporosis is a common disease that affects millions of patients worldwide and is most
common in menopausal women. The main characteristics of osteoporosis are low bone …

An overview of the molecular mechanisms contributing to musculoskeletal disorders in chronic liver disease: osteoporosis, sarcopenia, and osteoporotic sarcopenia

YJ Yang, DJ Kim - International journal of molecular sciences, 2021 - mdpi.com
The prevalence of osteoporosis and sarcopenia is significantly higher in patients with liver
disease than in those without liver disease and osteoporosis and sarcopenia negatively …

[PDF][PDF] Pharmacological agents and natural compounds: available treatments for osteoporosis.

M Martiniakova, M Babikova, R Omelka - Journal of Physiology & …, 2020 - jpp.krakow.pl
Osteoporosis, a systemic skeletal disease characterized by a decrease in bone mass and
deterioration of bone structure leading to an increased risk of fragility fractures, represents …

Bridging the Gap” Everything that Could Have Been Avoided If We Had Applied Gender Medicine, Pharmacogenetics and Personalized Medicine in the Gender …

D Gemmati, K Varani, B Bramanti, R Piva… - International journal of …, 2019 - mdpi.com
Gender medicine is the first step of personalized medicine and patient-centred care, an
essential development to achieve the standard goal of a holistic approach to patients and …

Lycopene and bone: An in vitro investigation and a pilot prospective clinical study

C Russo, Y Ferro, S Maurotti, MA Salvati… - Journal of translational …, 2020 - Springer
Background There are several effective therapies for osteoporosis but these agents might
cause serious adverse events. Lycopene intake could prevent bone loss, however studies …