Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

BACKGROUND Two developments in distinct fields are converging to create interest in
discovering small molecules from the human microbiome. First, the use of genomics to guide …

Covering: 1988 to 2012 This review presents recommended nomenclature for the
biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs) …

The early evolutionary history of the chloroplast lineage remains an open question. It is
widely accepted that the endosymbiosis that established the chloroplast lineage in …

Natural product libraries contain specialized metabolites derived from plants, animals, and
microorganisms that play a pivotal role in drug discovery due to their immense structural …

The cyanobacterial phylum encompasses oxygenic photosynthetic prokaryotes of a great
breadth of morphologies and ecologies; they play key roles in global carbon and nitrogen …

Covering: through 2014 Many organisms team up with microbes for defense against
predators, parasites, parasitoids, or pathogens. Here we review the described protective …

Covering 2000 to June 2015 This review discusses the biosynthesis of natural products that
are generated by trans-AT polyketide synthases, a family of catalytically versatile enzymes …

Marine sponges (phylum Porifera) often contain dense and diverse microbial communities,
which can constitute up to 35% of the sponge biomass. The genome of one sponge …

Marine planktonic cyanobacteria contributed to the widespread oxygenation of the oceans
towards the end of the Pre-Cambrian and their evolutionary origin represents a key …