Optical biosensor technology continues to be the method of choice for label‐free, real‐time
interaction analysis. But when it comes to improving the quality of the biosensor literature …

The current processing paradigm of large manufacturing facilities dedicated to single
product production is no longer an effective approach for best manufacturing practices …

Process analytical technology (PAT) has been gaining momentum in the biotech community
due to the potential for continuous real‐time quality assurance resulting in improved …

Monoclonal antibodies (mAbs) have become vitally important to modern medicine and are
currently one of the major biopharmaceutical products in development. However, the high …

Biomanufacturers are being incited by regulatory agencies to transition from a quality by
testing framework, where they extensively test their product after their production, to more of …

Soluble expression of recombinant proteins in E. coli is often done by translocation of the
product across the inner membrane (IM) into the periplasm, where it is retained by the outer …

Surface plasmon resonance (SPR) permits the quantitative analysis of therapeutic antibody
concentrations and impurities including bacteria, Protein A, Protein G and small molecule …

We report an innovative at-line method to monitor concentration of bioactive antibody (ie,
antibody with conserved antigen-binding activity) secreted during bioreactor culture by the …

Online and non‐invasive quantification of critical tissue engineering (TE) construct quality
attributes in TE bioreactors is indispensable for the cost‐effective up‐scaling and automation …

Influenza vaccine manufacturers lack tools, whatever the involved production bioprocess
(egg or cell-based), to precisely and accurately evaluate vaccine antigen content from …