Pathogen persistence in the respiratory tract is an important preoccupation, and of particular
relevance to infectious diseases such as tuberculosis. The equilibrium between elimination …

Worldwide, there is a rise in the prevalence of allergic diseases, and novel efficient
therapeutic approaches are still needed to alleviate disease burden. Prostaglandin D2 …

Background Idiopathic pulmonary fibrosis (IPF) is a disease with high 5-year mortality and
few therapeutic options. Prostaglandin (PG) E 2 exhibits antifibrotic properties and is …

When tumor cells are killed by targeted therapy, radiotherapy, or chemotherapy, they trigger
their primary tumor by releasing pro-inflammatory cytokines. Microenvironmental …

Background and Aims Phagocytosis (efferocytosis) of apoptotic neutrophils by macrophages
anchors the resolution of intestinal inflammation. Efferocytosis prevents secondary necrosis …

Asthma is the most common airway chronic disease with treatments aimed mainly to control
the symptoms. Adrenergic receptor agonists, corticosteroids and anti-leukotrienes have …

Pulmonary fibrosis is closely associated with the recruitment of fibroblasts from capillary
vessels with damaged endothelial cells, the epithelial mesenchymal transition (EMT) of type …

Prostaglandin (PG) D 2 has been in the focus of research for quite a long time, but its
biological effects and its roles in human disease are still not fully characterized. When in …

Simple Summary As a solid tumor, melanoma is not only a tumor mass of monolithic tumor
cells, but it also contains supporting stroma, extracellular matrix (ECM), and soluble …

Apoptotic cell clearance by phagocytes is essential in tissue homeostasis. We demonstrated
that conditioned medium (CM) from macrophages exposed to apoptotic cancer cells inhibits …