The immune system is a very diverse system of the host that evolved during evolution to
cope with various pathogens present in the vicinity of environmental surroundings inhabited …

BACKGROUND Fertility depends on a receptive state of the endometrium, influenced by
hormonal and anatomical adaptations, as well as the immune system. Local and systemic …

The mucosal immune system in the female reproductive tract (FRT) has evolved to meet the
unique requirements of dealing with sexually transmitted bacterial and viral pathogens …

Background Endometriosis is a multifactorial disease that mainly affects women of
reproductive age. The exact pathogenesis of this disease is still debatable. The role of …

Prostaglandins have a central role in many endocrine functions in mammals, including
regulation of the life span of the corpus luteum by prostaglandin F2α (PGF) and …

Infectious and sterile inflammatory diseases are correlated with increased levels of high
mobility group box 1 (HMGB1) in tissues and serum. Extracellular HMGB1 is known to …

Background The endometrium is commonly infected with bacteria leading to severe disease
of the uterus in cattle and humans. The endometrial epithelium is the first line of defence for …

The objective of this study was to examine the expression of TLR by human primary uterine
epithelial cells (UEC) and to determine whether exposure to the TLR agonist poly (I: C) …

The aim of this review is to discuss the role of Toll-like receptors at the maternal–fetal
interface and the capacity of trophoblast cells to initiate innate immune responses towards …

BACKGROUND: Pro-inflammatory chemokines that attract and cytokines that activate
immune cells contribute to normal physiological homeostasis in the female reproductive …