Sex differences in cardiovascular actions of the renin–angiotensin system

D Medina, D Mehay, AC Arnold - Clinical Autonomic Research, 2020 - Springer
Cardiovascular disease (CVD) remains a worldwide public health concern despite decades
of research and the availability of numerous targeted therapies. While the intrinsic …

[HTML][HTML] Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China

H Su, M Yang, C Wan, LX Yi, F Tang, HY Zhu, F Yi… - Kidney international, 2020 - Elsevier
Although the respiratory and immune systems are the major targets of Coronavirus Disease
2019 (COVID-19), acute kidney injury and proteinuria have also been observed. Currently …

[HTML][HTML] Sex differences in the renin-angiotensin-aldosterone system and its roles in hypertension, cardiovascular, and kidney diseases

SM Nwia, APO Leite, XC Li, JL Zhuo - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Cardiovascular disease is a pathology that exhibits well-researched biological sex
differences, making it possible for physicians to tailor preventative and therapeutic …

[HTML][HTML] Sexual dimorphic interplays between gut microbiota and antihypertensive drugs

P Bardhan, T Yang - Current Hypertension Reports, 2023 - Springer
Abstract Purpose of the Review The purpose of this study is to review the current literature
regarding gut microbiota in blood pressure regulation and its interactions with …

[HTML][HTML] Endocrine aspects of ACE2 regulation: RAAS, steroid hormones and SARS-CoV-2

MJ Young, CD Clyne… - Journal of …, 2020 - joe.bioscientifica.com
Coronavirus disease (COVID-19) is caused by a new strain of coronavirus, the severe acute
respiratory syndrome coronavirus 2 or SARS-CoV-2. At the time of writing, SARS-CoV-2 has …

[HTML][HTML] Blood ACE2 protein level correlates with COVID-19 severity

O Shevchuk, A Pak, S Palii, Y Ivankiv, K Kozak… - International Journal of …, 2023 - mdpi.com
ACE2's impact on the severity of COVID-19 is widely discussed but still controversial. To
estimate its role in aspects of the main risk factors and comorbidities, we involved post …

Collecting duct renin regulates potassium homeostasis in mice

C Xu, Y Chen, N Ramkumar, CJ Zou… - Acta …, 2023 - Wiley Online Library
Aim The kaliuretic action of the renin–angiotensin–aldosterone system (RAAS) is well
established as highlighted by hyperkalemia side effect of RAAS inhibitors but such action is …

[HTML][HTML] The role of macula densa nitric oxide synthase 1 beta splice variant in modulating tubuloglomerular feedback

R Liu, LA Juncos, Y Lu, J Wei, J Zhang… - Comprehensive …, 2023 - ncbi.nlm.nih.gov
Abnormalities in renal electrolyte and water excretion may result in inappropriate salt and
water retention, which facilitates the development and maintenance of hypertension, as well …

Smoking cessation avatar-led Acceptance and Commitment Therapy digital intervention: feasibility and acceptability in young adults

M Karekla, SN Savvides - Translational Behavioral Medicine, 2021 - academic.oup.com
Smoking remains a global concern especially among youth and smoking cessation
interventions have not been particularly successful with this age group. The aim of the …

[HTML][HTML] Nobiletin resolves left ventricular and renal changes in 2K-1C hypertensive rats

M Iampanichakul, A Poasakate, P Potue… - Scientific reports, 2022 - nature.com
This study investigated the effects of nobiletin on cardiorenal changes and the underlying
mechanisms involved in two-kidney, one-clip (2K-1C) hypertension. 2K-1C rats were treated …