[HTML][HTML] The search for gene-gene interactions in genome-wide association studies: challenges in abundance of methods, practical considerations, and biological …

MD Ritchie, K Van Steen - Annals of translational medicine, 2018 - ncbi.nlm.nih.gov
One of the primary goals in this era of precision medicine is to understand the biology of
human diseases and their treatment, such that each individual patient receives the best …

TPOT: A tree-based pipeline optimization tool for automating machine learning

RS Olson, JH Moore - Workshop on automatic machine …, 2016 - proceedings.mlr.press
As data science becomes more mainstream, there will be an ever-growing demand for data
science tools that are more accessible, flexible, and scalable. In response to this demand …

Evaluation of a tree-based pipeline optimization tool for automating data science

RS Olson, N Bartley, RJ Urbanowicz… - Proceedings of the genetic …, 2016 - dl.acm.org
As the field of data science continues to grow, there will be an ever-increasing demand for
tools that make machine learning accessible to non-experts. In this paper, we introduce the …

[HTML][HTML] PMLB: a large benchmark suite for machine learning evaluation and comparison

RS Olson, W La Cava, P Orzechowski, RJ Urbanowicz… - BioData mining, 2017 - Springer
Background The selection, development, or comparison of machine learning methods in
data mining can be a difficult task based on the target problem and goals of a particular …

Automating biomedical data science through tree-based pipeline optimization

RS Olson, RJ Urbanowicz, PC Andrews… - … 2016, Porto, Portugal …, 2016 - Springer
Over the past decade, data science and machine learning has grown from a mysterious art
form to a staple tool across a variety of fields in academia, business, and government. In this …

[HTML][HTML] Benchmarking relief-based feature selection methods for bioinformatics data mining

RJ Urbanowicz, RS Olson, P Schmitt, M Meeker… - Journal of biomedical …, 2018 - Elsevier
Modern biomedical data mining requires feature selection methods that can (1) be applied
to large scale feature spaces (eg 'omics' data),(2) function in noisy problems,(3) detect …

A review on methods for detecting SNP interactions in high-dimensional genomic data

S Uppu, A Krishna, RP Gopalan - IEEE/ACM transactions on …, 2016 - ieeexplore.ieee.org
In this era of genome-wide association studies (GWAS), the quest for understanding the
genetic architecture of complex diseases is rapidly increasing more than ever before. The …

ExSTraCS 2.0: description and evaluation of a scalable learning classifier system

RJ Urbanowicz, JH Moore - Evolutionary intelligence, 2015 - Springer
Algorithmic scalability is a major concern for any machine learning strategy in this age of 'big
data'. A large number of potentially predictive attributes is emblematic of problems in …

MACOED: a multi-objective ant colony optimization algorithm for SNP epistasis detection in genome-wide association studies

PJ Jing, HB Shen - Bioinformatics, 2014 - academic.oup.com
Motivation: The existing methods for genetic-interaction detection in genome-wide
association studies are designed from different paradigms, and their performances vary …

A differential evolution based feature combination selection algorithm for high-dimensional data

B Guan, Y Zhao, Y Yin, Y Li - Information Sciences, 2021 - Elsevier
Feature combination selection is used in object classification to select complementary
features that can produce a powerful combination. One active area of selecting feature …