1. INTRODUCTION The carbon− carbon bond forming reactions is one of the most important
reactions in organic chemistry, and therefore has been and remains an important and a …

Chiral molecules containing asymmetric carbon centers bonded with nitrogen are ubiquitous
in nature and also form important structural fragments in both natural and man-made …

Catalytic asymmetric synthesis has been one of the most active research areas in chemistry
(Nobel Prize in 2001). The development of efficient chiral catalysts plays a crucial role in …

Enantioselective synthesis with small-molecule chiral hydrogen-bond donors has emerged
as a frontier of research in the field of asymmetric catalysis. Organic chemists have …

The fundamental role of the Lewis-acid catalyst lies in the activation of the CdX bond (X) O,
NR, CR2), thereby decreasing the LUMO energy and promoting nucleophilic addition to the …

Organic synthesis is one of the most successful and useful disciplines of science and mainly
involves the construction of carbon-carbon bond (s) and carbon-heteroatom bond (s) and …

Hydrogen bonding is responsible for the structure of much of the world around us. The
unusual and complex properties of bulk water, the ability of proteins to fold into stable three …

Abstract The legacy of Gilbert Newton Lewis (1875–1946) pervades the lexicon of chemical
bonding and reactivity. The power of his concept of donor–acceptor bonding is evident in the …

Asymmetric organocatalysis is becoming one of the main tools for the synthesis of chiral
compounds that are needed as medicines, crop protection agents, and other bioactive …

Hydrogen bond catalysis and Brønsted acid catalysis are rapidly growing areas in
organocatalysis. A number of chiral acid catalysts has been developed recently. Recent …