Arteriovenous malformations are a vascular anomaly typically present at birth, characterized
by an abnormal connection between an artery and a vein (bypassing the capillaries). These …

It is well established that control of vascular morphogenesis and homeostasis is regulated
by vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), Delta-like 4 …

Abstract Loss-of-function (LOF) mutations in the endothelial cell (EC)-enriched gene
endoglin (ENG) cause the human disease hereditary haemorrhagic telangiectasia-1 …

Hereditary hemorrhagic telangiectasia (HHT) is a Mendelian disease characterized by
vascular malformations (VMs) including visceral arteriovenous malformations and mucosal …

Hereditary hemorrhagic telangiectasia (HHT) is a genetic disorder characterized by a multi-
systemic vascular dysplasia and hemorrhage. The precise factors leading to these vascular …

Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disorder
that leads to abnormal connections between arteries and veins termed arteriovenous …

Objective Brain arteriovenous malformations (bAVMs) are a leading cause of hemorrhagic
stroke and neurological deficits in children and young adults, however, no pharmacological …

Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant genetic disorder
that presents with telangiectases in skin and mucosae, and arteriovenous malformations …

Brain arteriovenous malformations (AVMs) are a disorder wherein abnormal, enlarged blood
vessels connect arteries directly to veins, without an intervening capillary bed. AVMs are one …

Background: Hereditary hemorrhagic telangiectasia is an autosomal dominant vascular
disorder caused by heterozygous, loss-of-function mutations in 4 transforming growth factor …