MJ Goumans, A Zwijsen… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
It is well established that control of vascular morphogenesis and homeostasis is regulated by vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), Delta-like 4 …
Y Jin, L Muhl, M Burmakin, Y Wang, AC Duchez… - Nature cell …, 2017 - nature.com
Abstract Loss-of-function (LOF) mutations in the endothelial cell (EC)-enriched gene endoglin (ENG) cause the human disease hereditary haemorrhagic telangiectasia-1 …
DA Snellings, CJ Gallione, DS Clark, NT Vozoris… - The American Journal of …, 2019 - cell.com
Hereditary hemorrhagic telangiectasia (HHT) is a Mendelian disease characterized by vascular malformations (VMs) including visceral arteriovenous malformations and mucosal …
Hereditary hemorrhagic telangiectasia (HHT) is a genetic disorder characterized by a multi- systemic vascular dysplasia and hemorrhage. The precise factors leading to these vascular …
AM Crist, AR Lee, NR Patel, DE Westhoff… - Angiogenesis, 2018 - Springer
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disorder that leads to abnormal connections between arteries and veins termed arteriovenous …
Objective Brain arteriovenous malformations (bAVMs) are a leading cause of hemorrhagic stroke and neurological deficits in children and young adults, however, no pharmacological …
C Bernabeu, P Bayrak-Toydemir, J McDonald… - Journal of Clinical …, 2020 - mdpi.com
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant genetic disorder that presents with telangiectases in skin and mucosae, and arteriovenous malformations …
K Soon, M Li, R Wu, A Zhou, N Khosraviani, WD Turner… - Biomaterials, 2022 - Elsevier
Brain arteriovenous malformations (AVMs) are a disorder wherein abnormal, enlarged blood vessels connect arteries directly to veins, without an intervening capillary bed. AVMs are one …