SNARE proteins in membrane trafficking
T Wang, L Li, W Hong - Traffic, 2017 - Wiley Online Library
SNAREs are the core machinery mediating membrane fusion. In this review, we provide an
update on the recent progress on SNAREs regulating membrane fusion events, especially …
update on the recent progress on SNAREs regulating membrane fusion events, especially …
Structure and function of longin SNAREs
F Daste, T Galli, D Tareste - Journal of cell science, 2015 - journals.biologists.com
Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins
constitute the core membrane fusion machinery of intracellular transport and intercellular …
constitute the core membrane fusion machinery of intracellular transport and intercellular …
Non-canonical role of the SNARE protein Ykt6 in autophagosome-lysosome fusion
The autophagosomal SNARE Syntaxin17 (Syx17) forms a complex with Snap29 and
Vamp7/8 to promote autophagosome-lysosome fusion via multiple interactions with the …
Vamp7/8 to promote autophagosome-lysosome fusion via multiple interactions with the …
Endosomal and phagosomal SNAREs
I Dingjan, PTA Linders, DRJ Verboogen… - Physiological …, 2018 - journals.physiology.org
The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein
family is of vital importance for organelle communication. The complexing of cognate …
family is of vital importance for organelle communication. The complexing of cognate …
A SNARE geranylgeranyltransferase essential for the organization of the Golgi apparatus
R Shirakawa, S Goto‐Ito, K Goto, S Wakayama… - The EMBO …, 2020 - embopress.org
Protein prenylation is essential for many cellular processes including signal transduction,
cytoskeletal reorganization, and membrane trafficking. Here, we identify a novel type of …
cytoskeletal reorganization, and membrane trafficking. Here, we identify a novel type of …
Protein prenyltransferases and their inhibitors: structural and functional characterization
A Marchwicka, D Kamińska, M Monirialamdari… - International Journal of …, 2022 - mdpi.com
Protein prenylation is a post-translational modification controlling the localization, activity,
and protein–protein interactions of small GTPases, including the Ras superfamily. This …
and protein–protein interactions of small GTPases, including the Ras superfamily. This …
Stress-induced cellular clearance is mediated by the SNARE protein ykt6 and disrupted by α-Synuclein
Age-related neurodegenerative disorders are characterized by a slow, persistent
accumulation of aggregated proteins. Although cells can elicit physiological responses to …
accumulation of aggregated proteins. Although cells can elicit physiological responses to …
The importance of lipid modified proteins in plants
PA Hemsley - New Phytologist, 2015 - Wiley Online Library
Membranes have long been known to act as more than physical barriers within and between
plant cells. Trafficking of membrane proteins, signalling from and across membranes …
plant cells. Trafficking of membrane proteins, signalling from and across membranes …
Impaired autophagic-lysosomal fusion in Parkinson's patient midbrain neurons occurs through loss of ykt6 and is rescued by farnesyltransferase inhibition
C Pitcairn, N Murata, AJ Zalon, I Stojkovska… - Journal of …, 2023 - Soc Neuroscience
Macroautophagy is a catabolic process that coordinates with lysosomes to degrade
aggregation-prone proteins and damaged organelles. Loss of macroautophagy …
aggregation-prone proteins and damaged organelles. Loss of macroautophagy …
Upregulation of Cellular Palmitoylation Mitigates α‐Synuclein Accumulation and Neurotoxicity
ABSTRACT Background Synucleinopathies, including Parkinson's disease (PD), are
characterized by α‐synuclein (αS) cytoplasmic inclusions. αS‐dependent vesicle‐trafficking …
characterized by α‐synuclein (αS) cytoplasmic inclusions. αS‐dependent vesicle‐trafficking …