Cross-feeding in the gut microbiome: ecology and mechanisms

EJ Culp, AL Goodman - Cell host & microbe, 2023 - cell.com
Microbial communities are shaped by positive and negative interactions ranging from
competition to mutualism. In the context of the mammalian gut and its microbial inhabitants …

Metabolism of dietary and microbial vitamin B family in the regulation of host immunity

K Yoshii, K Hosomi, K Sawane, J Kunisawa - Frontiers in nutrition, 2019 - frontiersin.org
Vitamins are micronutrients that have physiological effects on various biological responses,
including host immunity. Therefore, vitamin deficiency leads to increased risk of developing …

Enzymatic carbon–sulfur bond formation in natural product biosynthesis

KL Dunbar, DH Scharf, A Litomska… - Chemical …, 2017 - ACS Publications
Sulfur plays a critical role for the development and maintenance of life on earth, which is
reflected by the wealth of primary metabolites, macromolecules, and cofactors bearing this …

Biological Properties of Vitamins of the B-Complex, Part 1: Vitamins B1, B2, B3, and B5

M Hrubša, T Siatka, I Nejmanová, M Vopršalová… - Nutrients, 2022 - mdpi.com
This review summarizes the current knowledge on essential vitamins B1, B2, B3, and B5.
These B-complex vitamins must be taken from diet, with the exception of vitamin B3, that can …

Systematic genome assessment of B-vitamin biosynthesis suggests co-operation among gut microbes

S Magnúsdóttir, D Ravcheev, V de Crécy-Lagard… - Frontiers in …, 2015 - frontiersin.org
The human gut microbiota supplies its host with essential nutrients, including B-vitamins.
Using the PubSEED platform, we systematically assessed the genomes of 256 common …

Exploiting rRNA operon copy number to investigate bacterial reproductive strategies

BRK Roller, SF Stoddard, TM Schmidt - Nature microbiology, 2016 - nature.com
The potential for rapid reproduction is a hallmark of microbial life, but microbes in nature
must also survive and compete when growth is constrained by resource availability …

Radical S-Adenosylmethionine Enzymes

JB Broderick, BR Duffus, KS Duschene… - Chemical …, 2014 - ACS Publications
It was once widely held that nearly all reactions in biology were catalyzed via mechanisms
involving paired electron species. Beginning approximately 40 years ago, this paradigm was …

The importance of thiamine (vitamin B1) in humans

M Mrowicka, J Mrowicki, G Dragan… - Bioscience …, 2023 - portlandpress.com
Abstract Thiamine (thiamin, B1) is a vitamin necessary for proper cell function. It exists in a
free form as a thiamine, or as a mono-, di-or triphosphate. Thiamine plays a special role in …

Methylerythritol 4-phosphate (MEP) pathway metabolic regulation

A Banerjee, TD Sharkey - Natural product reports, 2014 - pubs.rsc.org
Covering: up to February 2014 The methylerythritol 4-phosphate (MEP) pathway is the
recently discovered source of isoprenoid precursors isopentenyl diphosphate (IDP) and …

The methylerythritol phosphate pathway to isoprenoids

A Frank, M Groll - Chemical Reviews, 2017 - ACS Publications
Isoprenoids constitute one of the most diverse classes of natural products. As a compound
class, they are essential to basic metabolic processes including cell-wall biosynthesis, post …