Physiology and physical chemistry of bile acids

MC Di Gregorio, J Cautela, L Galantini - International journal of molecular …, 2021 - mdpi.com
Bile acids (BAs) are facial amphiphiles synthesized in the body of all vertebrates. They
undergo the enterohepatic circulation: they are produced in the liver, stored in the …

Self-assembly of bile salts and their mixed aggregates as building blocks for smart aggregates

PY Parekh, VI Patel, MR Khimani, P Bahadur - Advances in Colloid and …, 2023 - Elsevier
The present communication offers a comprehensive overview of the self-assembly of bile
salts emphasizing their mixed smart aggregates with a variety of amphiphiles. Using an …

Pluronic F68 micelles as carriers for an anti-inflammatory drug: A rheological and scattering investigation

NA Di Spirito, N Grizzuti, V Lutz-Bueno, G Urciuoli… - Langmuir, 2024 - ACS Publications
Age-long ambition of medical scientists has always been advancement in healthcare and
therapeutic medicine. Biomedical research indeed claims paramount importance in …

Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients

E Izquierdo, P Proszek, G Pericoli… - Neuro-oncology …, 2021 - academic.oup.com
Background The use of liquid biopsy is of potential high importance for children with high
grade (HGG) and diffuse midline gliomas (DMG), particularly where surgical procedures are …

Degradation of drug delivery nanocarriers and payload release: A review of physical methods for tracing nanocarrier biological fate

PM Perrigue, RA Murray, A Mielcarek, A Henschke… - Pharmaceutics, 2021 - mdpi.com
Nanoformulations offer multiple advantages over conventional drug delivery, enhancing
solubility, biocompatibility, and bioavailability of drugs. Nanocarriers can be engineered with …

A novel multifunctional NCQDs-based injectable self-crosslinking and in situ forming hydrogel as an innovative stimuli responsive smart drug delivery system for …

S Türk, I Altınsoy, GÇ Efe, M Ipek, M Özacar… - Materials Science and …, 2021 - Elsevier
In this work, we offer an easy approach to develop a novel injectable, pH sensitive and in
situ smart drug delivery system for use in cancer treatments. The developed hydrogels …

[HTML][HTML] Self-assembled chitosan-sodium usnate drug delivery nanosystems: Synthesis, characterization, stability studies, in vitro cytotoxicity and in vivo …

B Brugnoli, A Mariano, B Simonis, C Bombelli… - Carbohydrate Polymer …, 2023 - Elsevier
Polymers are among the most studied materials as drug carriers, due to their tunable
chemical structure and ability to self-assemble to give different types of nanostructures. In …

[HTML][HTML] Determination of the optimal pH for doxorubicin encapsulation in polymeric micelles

L Desiderio, NS Gjerde, E Tasca, L Galantini… - Journal of Colloid and …, 2024 - Elsevier
Hypothesis The anticancer drug doxorubicin hydrochloride (DX) shows a high solubility in
aqueous media thanks to the positive charge in the ammonium group. This feature …

Role of Unimers to Polymersomes Transition in Pluronic Blends for Controlled and Designated Drug Conveyance

D Patel, N Tripathi, P Vaswani… - The Journal of …, 2024 - ACS Publications
This study investigates the nanoscale self-assembly from mixtures of two symmetrical poly
(ethylene oxide)-poly (propylene oxide)-pol (ethylene oxide)(PEO–PPO-PEO) block …

Absorption behavior of doxorubicin hydrochloride in visible region in different environments: A combined experimental and computational study

CG Chen, AN Nardi, M Giustini… - Physical Chemistry …, 2022 - pubs.rsc.org
The experimental absorption measurements in the interval 350–600 nm (Vis), molecular
dynamics simulations, quantum-mechanics calculations and an advanced molecular …