Toll-like receptors and toll-like receptor-targeted immunotherapy against glioma
Y Xun, H Yang, B Kaminska, H You - Journal of hematology & oncology, 2021 - Springer
Glioma represents a fast proliferating and highly invasive brain tumor which is resistant to
current therapies and invariably recurs. Despite some advancements in anti-glioma …
current therapies and invariably recurs. Despite some advancements in anti-glioma …
[HTML][HTML] Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging
R Bogeska, AM Mikecin, P Kaschutnig, M Fawaz… - Cell stem cell, 2022 - cell.com
Hematopoietic stem cells (HSCs) mediate regeneration of the hematopoietic system
following injury, such as following infection or inflammation. These challenges impair HSC …
following injury, such as following infection or inflammation. These challenges impair HSC …
Bone marrow immune microenvironment in myelodysplastic syndromes
O Kouroukli, A Symeonidis, P Foukas, MK Maragkou… - Cancers, 2022 - mdpi.com
Simple Summary The bone marrow (BM) microenvironment regulates normal hematopoiesis
and exerts variable activity in various inflammatory, toxic, autoimmune, or neoplastic …
and exerts variable activity in various inflammatory, toxic, autoimmune, or neoplastic …
Biophysical cues of bone marrow-inspired scaffolds regulate hematopoiesis of hematopoietic stem and progenitor cells
Hematopoietic stem cells (HSCs) are adult multipotential stem cells with the capacity to
differentiate into all blood cells and immune cells, which are essential for maintaining …
differentiate into all blood cells and immune cells, which are essential for maintaining …
Always stressed but never exhausted: how stem cells in myeloid neoplasms avoid extinction in inflammatory conditions
HG Zhao, M Deininger - Blood, The Journal of the American …, 2023 - ashpublications.org
Chronic or recurrent episodes of acute inflammation cause attrition of normal hematopoietic
stem cells (HSCs) that can lead to hematopoietic failure but they drive progression in …
stem cells (HSCs) that can lead to hematopoietic failure but they drive progression in …
MiR‐9‐enriched mesenchymal stem cells derived exosomes prevent cystitis‐induced bladder pain via suppressing TLR4/NLRP3 pathway in interstitial cystitis mice
X Cui, X Bi, X Zhang, Z Zhang, Q Yan… - Immunity …, 2024 - Wiley Online Library
Background Inflammatory response of central nervous system is an important component
mechanism in the bladder pain of interstitial cystitis/bladder pain syndrome (IC/BPS) …
mechanism in the bladder pain of interstitial cystitis/bladder pain syndrome (IC/BPS) …
A gut instinct on leukaemia: A new mechanistic hypothesis for microbiota-immune crosstalk in disease progression and relapse
Despite significant advances in the treatment of Chronic Myeloid and Acute Lymphoblastic
Leukaemia (CML and ALL, respectively), disease progression and relapse remain a major …
Leukaemia (CML and ALL, respectively), disease progression and relapse remain a major …
Effects of a yeast cell wall product on the performance of broiler chickens and PGC-1α, TLR4, IL-10 and PPARγ genes expression
M Sedghi, I Mohammadi, Z Sarrami… - Italian Journal of …, 2022 - Taylor & Francis
The current study was conducted to evaluate the effects of a yeast cell wall product (YCWP)
on the performance, the population of Lactobacillus and coliform bacteria and PGC-1α …
on the performance, the population of Lactobacillus and coliform bacteria and PGC-1α …
Altered 3D genome reorganization mediates precocious myeloid differentiation of aged hematopoietic stem cells in inflammation
X Cui, Y Dong, Q Zhan, Y Huang, Q Zhu… - Science China Life …, 2024 - Springer
Inflammation is a driving force of hematopoietic stem cells (HSCs) aging, causing
irreversible exhaustion of functional HSCs. However, the underlying mechanism of HSCs …
irreversible exhaustion of functional HSCs. However, the underlying mechanism of HSCs …
A Perfect Storm: The Convergence of Aging, Human Immunodeficiency Virus Infection, and Inflammasome Dysregulation
S Thirugnanam, N Rout - Current Issues in Molecular Biology, 2024 - mdpi.com
The emergence of combination antiretroviral therapy (cART) has greatly transformed the life
expectancy of people living with HIV (PWH). Today, over 76% of the individuals with HIV …
expectancy of people living with HIV (PWH). Today, over 76% of the individuals with HIV …