Intestinal barrier function–non-alcoholic fatty liver disease interactions and possible role of gut microbiota

Y Cui, Q Wang, R Chang, X Zhou… - Journal of agricultural and …, 2019 - ACS Publications
Non-alcoholic fatty liver disease (NAFLD) is a metabolic stress liver injury that is closely
related to obesity, insulin resistance, type 2 diabetes, atherosclerosis, and metabolic …

Mitochondrial abnormalities in neurodegenerative models and possible interventions: Focus on Alzheimer's disease, Parkinson's disease, Huntington's disease

P Pantiya, C Thonusin, N Chattipakorn… - Mitochondrion, 2020 - Elsevier
Mitochondrial abnormalities in the brain are considered early pathological changes in
neurogenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD) and …

[HTML][HTML] Effects of a 6-month multi-strain probiotics supplementation in endotoxemic, inflammatory and cardiometabolic status of T2DM patients: A randomized, double …

S Sabico, A Al-Mashharawi, NM Al-Daghri, K Wani… - Clinical nutrition, 2019 - Elsevier
Objective The aim of this trial was to characterize the beneficial effects of probiotics on
decreasing endotoxin levels and other cardiometabolic parameters in Arab patients with …

Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes

RR Rodrigues, M Gurung, Z Li… - Nature …, 2021 - nature.com
Western diet (WD) is one of the major culprits of metabolic disease including type 2 diabetes
(T2D) with gut microbiota playing an important role in modulating effects of the diet. Herein …

Lactobacillus paracasei HII01, xylooligosaccharides, and synbiotics reduce gut disturbance in obese rats

P Thiennimitr, S Yasom, W Tunapong, T Chunchai… - Nutrition, 2018 - Elsevier
Objectives The beneficial effects of pro-, pre-, and synbiotics on obesity with insulin
resistance have been reported previously. However, the strain-specific effect of probiotics …

Mitochondrial dysfunction promotes microbial composition that negatively impacts on ulcerative colitis development and progression

A Peña-Cearra, D Song, J Castelo, A Palacios… - NPJ biofilms and …, 2023 - nature.com
Recent evidence demonstrates potential links between mitochondrial dysfunction and
inflammatory bowel diseases (IBD). In addition, bidirectional interactions between the …

Influence of cardiometabolic comorbidities on myocardial function, infarction, and cardioprotection: Role of cardiac redox signaling

I Andreadou, A Daiber, GF Baxter, MF Brizzi… - Free Radical Biology …, 2021 - Elsevier
The morbidity and mortality from cardiovascular diseases (CVD) remain high. Metabolic
diseases such as obesity, hyperlipidemia, diabetes mellitus (DM), non-alcoholic fatty liver …

Implications of gut microbiota in complex human diseases

D Yu, X Meng, WM de Vos, H Wu, X Fang… - International journal of …, 2021 - mdpi.com
Humans, throughout the life cycle, from birth to death, are accompanied by the presence of
gut microbes. Environmental factors, lifestyle, age and other factors can affect the balance of …

Preventive Effect and Molecular Mechanism of Lactobacillus rhamnosus JL1 on Food-Borne Obesity in Mice

M Yang, J Zheng, X Zong, X Yang, Y Zhang, C Man… - Nutrients, 2021 - mdpi.com
Probiotics can prevent obesity and related metabolic complications. In our study, the
protective effect and molecular mechanism of Lactobacillus rhamnosus JL1 (separated from …

Diabetes and the gut microbiome

WL Lau, T Tran, CM Rhee, K Kalantar-Zadeh… - Seminars in …, 2021 - Elsevier
Gut dysbiosis in diabetes mellitus is associated with decreased short-chain fatty acids and
epithelial barrier disruption. Microbial-derived toxins move across the “leaky gut” and incur …