Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …

Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively
studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin …

Akt is a serine/threonine kinase and it participates in the key role of the PI3K signaling
pathway. The Akt can be activated by a wide range of growth signals and the biochemical …

Brain-derived neurotrophic factor (BDNF) is one of the most widely distributed and
extensively studied neurotrophins in the mammalian brain. Among its prominent functions …

Human biomonitoring (HBM) studies have demonstrated widespread and daily exposure to
bisphenol A (BPA). Moreover, BPA structural analogues (eg BPS, BPF, BPAF), used as BPA …

Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

Recently researchers proposed the term 'Type-3-Diabetes' for Alzheimer's disease (ad)
because of the shared molecular and cellular features among Type-1-Diabetes, Type-2 …

How do antidepressants elicit an antidepressant response? Here, we review accumulating
evidence that the neurotrophin brain-derived neurotrophic factor (BDNF) serves as a …

Excitotoxicity, the specific type of neurotoxicity mediated by glutamate, may be the missing
link between ischemia and neuronal death, and intervening the mechanistic steps that lead …