Smooth muscle cell migration occurs during vascular development, in response to vascular
injury, and during atherogenesis. Many proximal signals and signal transduction pathways …

The fibroblast growth factor (FGF) family consists of at least 15 structurally related
polypeptide growth factors. Their expression is controlled at the levels of transcription …

Urokinase plasminogen activator (uPA) is thought to exert its effects on cell growth,
adhesion, and migration by mechanisms involving proteolysis and interaction with its cell …

Vascular diseases, such as atherosclerosis, thromboembolic disorders and stroke, in
addition to surgical procedures such as restenosis, all share the plasminogen activator …

Urokinase (uPA)‐induced signaling in human vascular smooth muscle cells (VSMC) elicits
important cellular functional responses, such as cell migration and proliferation. However …

Cancer invasion is regulated by cell surface proteinases and adhesion molecules.
Interaction between specific cell surface molecules such as urokinase plasminogen activator …

A wide variety of disorders are associated with an imbalance in the plasminogen activator
system, including inflammatory diseases, atherosclerosis, intimal hyperplasia, the response …

Clinical studies have indicated that high plasma levels of fibrinogen, or decreased
fibrinolytic potential, are conducive to an increased risk of cardiovascular disease. Other …

This review considers cellular and molecular mechanisms of the involvement of
plasminogen activators in extracellular proteolysis and cell migration and proliferation. The …

The structural basis of the interaction between single-chain urokinase-type plasminogen
activator (scuPA) and its receptor (uPAR) is incompletely defined. Several observations …