Chimeric antigen receptor T-cell therapy in autoimmune diseases
J Liu, Y Zhao, H Zhao - Frontiers in Immunology, 2024 - frontiersin.org
The administration of T cells that have been modified to carry chimeric antigen receptors
(CARs) aimed at B cells has been an effective strategy in treating B cell malignancies. This …
(CARs) aimed at B cells has been an effective strategy in treating B cell malignancies. This …
Immunotherapy strategy for systemic autoimmune diseases: betting on CAR-T cells and antibodies
Systemic autoimmune diseases (SAIDs), such as systemic lupus erythematosus (SLE),
systemic sclerosis (SSc) and rheumatoid arthritis (RA), are fully related to the unregulated …
systemic sclerosis (SSc) and rheumatoid arthritis (RA), are fully related to the unregulated …
CAR T treatment beyond cancer: Hope for immunomodulatory therapy of non-cancerous diseases
Z Yang, Y Liu, H Zhao - Life Sciences, 2024 - Elsevier
Engineering a patient's own T cells to accurately identify and eliminate cancer cells has
effectively cured individuals afflicted with previously incurable hematologic cancers. These …
effectively cured individuals afflicted with previously incurable hematologic cancers. These …
The advent of chimeric antigen receptor T Cell therapy in recalibrating immune balance for rheumatic autoimmune disease treatment
Q Guo, J Li, J Wang, L Li, J Wei, L Zhang - Frontiers in Pharmacology, 2024 - frontiersin.org
CAR-T cell therapy, a cutting-edge cellular immunotherapy with demonstrated efficacy in
treating hematologic malignancies, also exhibits significant promise for addressing …
treating hematologic malignancies, also exhibits significant promise for addressing …
A Review of Antisynthetase Syndrome-Associated Interstitial Lung Disease
P Patel, JM Marinock, A Ajmeri, LH Brent - International Journal of …, 2024 - mdpi.com
Our objective in this review article is to present a clinical case of a patient with
antisynthetase syndrome (ASyS) and provide an overview of the pathogenesis, classification …
antisynthetase syndrome (ASyS) and provide an overview of the pathogenesis, classification …
New and emerging therapies for systemic lupus erythematosus
E Papachristodoulou, VC Kyttaris - Clinical Immunology, 2024 - Elsevier
Abstract Systemic Lupus Erythematosus (SLE) and lupus nephritis treatment is still based on
non-specific immune suppression despite the first biological therapy for the disease having …
non-specific immune suppression despite the first biological therapy for the disease having …
Nefrite Lúpica: Opções Terapêuticas
JPC Moreira - 2024 - search.proquest.com
Introdução: A nefrite lúpica afeta cerca de 40% da população com lúpus eritematoso
sistémico e é uma complicação severa desta patologia autoimune. O seu tratamento baseia …
sistémico e é uma complicação severa desta patologia autoimune. O seu tratamento baseia …