Abstract Multi-Drug Resistant (MDR) Pseudomonas aeruginosa is one of the most important
bacterial pathogens that causes infection with a high mortality rate due to resistance to …

Microbial communities enmeshed in a matrix of macromolecules, termed as biofilms, are the
natural setting of bacteria. Exopolysaccharide is a critical matrix component of biofilms …

Bacteriophages of the Podoviridae family often exhibit so-called depolymerases as
structural components of the virion. These enzymes appear as tail spike proteins (TSPs) …

Pseudomonas aeruginosa, a Gram-negative bacterium, is one of the major pathogens
implicated in human opportunistic infection and a common cause of clinically persistent …

In addition to specific antibiotic resistance, the formation of bacterial biofilm causes another
level of complications in attempts to eradicate pathogenic or harmful bacteria, including …

One of the potential antibiofilm strategies is to use lytic phages and phage-derived
polysaccharide depolymerases. The idea is to uncover bacteria embedded in the biofilm …

Biofilm formation is one of the main causes of increased antibiotic resistance in
Acinetobacter baumannii infections. Bacteriophages and their derivatives, such as tail …

Pseudomonas aeruginosa is an aerobic Gram-negative rod-shaped bacterium with a
comparatively large genome and an impressive genetic capability allowing it to grow in a …

Bacteriophage-encoded depolymerases are responsible for degrading capsular
polysaccharides (CPS), lipopolysaccharides (LPS), and exopolysaccharides (EPS) of the …

In cystic fibrosis (CF), pulmonary infection with Pseudomonas aeruginosa is a cause of
increased morbidity and mortality, especially in patients for whom infection becomes chronic …