[HTML][HTML] A cross-species comparative approach to assessing multi-and transgenerational effects of endocrine disrupting chemicals
A wide range of chemicals have been identified as endocrine disrupting chemicals (EDCs)
in vertebrate species. Most studies of EDCs have focused on exposure of both male and …
in vertebrate species. Most studies of EDCs have focused on exposure of both male and …
Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes
AR Ringel, Q Szabo, AM Chiariello, K Chudzik… - Cell, 2022 - cell.com
Regulatory landscapes drive complex developmental gene expression, but it remains
unclear how their integrity is maintained when incorporating novel genes and functions …
unclear how their integrity is maintained when incorporating novel genes and functions …
Zebrafish transposable elements show extensive diversification in age, genomic distribution, and developmental expression
There is considerable interest in understanding the effect of transposable elements (TEs) on
embryonic development. Studies in humans and mice are limited by the difficulty of working …
embryonic development. Studies in humans and mice are limited by the difficulty of working …
Epigenetic regulation of endothelial cell lineages during zebrafish development—new insights from technical advances
Epigenetic regulation is integral in orchestrating the spatiotemporal regulation of gene
expression which underlies tissue development. The emergence of new tools to assess …
expression which underlies tissue development. The emergence of new tools to assess …
Integrative mapping of the dog epigenome: Reference annotation for comparative intertissue and cross-species studies
Dogs have become a valuable model in exploring multifaceted diseases and biology
relevant to human health. Despite large-scale dog genome projects producing high-quality …
relevant to human health. Despite large-scale dog genome projects producing high-quality …
Promoter repression and 3D-restructuring resolves divergent developmental gene expression in TADs
AR Ringel, Q Szabo, AM Chiariello, K Chudzik… - BioRxiv, 2021 - biorxiv.org
Cohesin loop extrusion facilitates precise gene expression by continuously driving
promoters to sample all enhancers located within the same topologically-associated domain …
promoters to sample all enhancers located within the same topologically-associated domain …