Combination therapy and nanotechnology offer a promising therapeutic method in cancer
treatment. By improving drug's pharmacokinetics, nanoparticulate systems increase the …

Breast cancer is the most frequently happening cancer and the most typical cancer death
among females. Despite the crucial progress in breast cancer therapy by using …

Docetaxel (DTX) is found to be very effective against glioma cell in vitro. However, in vivo
passage of DTX through BBB is extremely difficult due to the physicochemical and …

Background: Silybin (Sb) is the major flavolignan of the extract of Silybum marianum. It is
used for the treatment of various acute and chronic liver toxicities, inflammation, fibrosis and …

Apigenin has gained interest recently among researchers as a potential chemotherapeutic
agent in cancer, including colorectal cancer, due to its established antiproliferative activity in …

This study aimed to deliver a potential water-soluble antiviral drug (sofosbuvir) through
optimized vesicular lipid nanocarriers (LNs) to the rat brain as a novel strategy against viral …

Nonsteroidal anti-inflammatory drugs (NSAIDs), inhibitors of cyclooxygenase-2, an enzyme
involved in the formation of anti-inflammatory prostaglandin PGE2, are the most common …

The aim of this study was to examine the effectiveness of alanine-proline-arginine-proline-
glycine (APRPG) peptide–conjugated PEGylated cationic liposomes–encapsulated …

Nanotechnology—the construction and use of functional structures designed from atomic or
molecular scale—is expected to favor all fields of medicine, with oncology being the most …

Deoxyschizandrin (DS) is a bioactive benzocyclooctadiene lignan found in the fruit of
Schisandra chinensis. However, poor bioavailability and non-specificity of DS frequently …