Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …

Alzheimer disease (AD) is characterized by progressive cognitive decline in older
individuals accompanied by the presence of two pathological protein aggregates—amyloid …

Parkinson's disease (PD) is characterized by a progressive loss of dopaminergic neurons.
Exercise has been reported to slow the clinical progression of PD. We evaluated the …

Sex and gender—biological and social constructs—significantly impact the prevalence of
protective and risk factors, influencing the burden of Alzheimer's disease (AD; amyloid beta …

Alzheimer's disease is a devastating neurodegenerative disorder that poses a significant
societal burden. Approval of anti-amyloid antibody therapies is a significant milestone for …

Physical activity may offset cognitive decline and dementia, but the molecular mechanisms
by which it promotes neuroprotection remain elusive. In the absence of disease-modifying …

Alzheimer's disease (AD) is characterised by synaptic dysfunction accompanied by the
microscopically visible accumulation of pathological protein deposits and cellular dystrophy …

Brain vascular health appears to be critical for preventing the development of amyotrophic
lateral sclerosis (ALS) and slowing its progression. ALS patients often demonstrate …

Exercise preconditioning has attracted extensive attention to induce endogenous
neuroprotection and has become the hotspot in neurotherapy. The training exercise is given …

Abstract Alzheimer's disease (AD), similar to AD-related dementias, is characterized by
impaired/lost neuronal structures and functions due to a long progression of …