Prostate cancer is characterized by a high degree of heterogeneity, which poses a major
challenge to precision therapy and drug development. In this review, we discuss how …

Though cell size varies between different cells and across species, the nuclear-to-
cytoplasmic (N/C) ratio is largely maintained across species and within cell types. A cell …

Cell division and cell death are fundamental processes governing growth and development
across the tree of life. This relationship represents an evolutionary link between cell cycle …

Human cytomegalovirus (HCMV) is a herpesvirus that infects between 40% and 95% of the
population worldwide, usually without symptoms. The host immune response keeps the …

DNA replication during cell proliferation is 'vertical'copying, which reproduces an initial
amount of genetic information. Polyploidy, which results from whole-genome duplication, is …

In response to adverse environmental conditions, embryonic development may reversibly
cease, a process termed diapause. Recent reports connect this phenomenon with the non …

Faithful eucaryotic cell division requires spatio-temporal orchestration of multiple sequential
events. To ensure the dynamic nature of these molecular and morphological transitions, a …

Over 50 years of cancer research has resulted in the generation of massive amounts of
information, but relatively little progress has been made in the treatment of patients with solid …

Polyploid cells demonstrate biological plasticity and stress adaptation in evolution;
development; and pathologies, including cardiovascular diseases, neurodegeneration, and …

Background Reactive oxygen species (ROS) are implicated in cancer therapy and as drivers
of microenvironmental tumour cell adaptations. Medical gas plasma is a multi-ROS …