This review presents the comprehensive knowledge about the bidirectional relationship
between polyphenols and the gut microbiome. The first part is related to polyphenols' …

Major lignans of sesame sesamin and sesamolin are benzodioxol--substituted furofurans.
Sesamol, sesaminol, its epimers, and episesamin are transformation products found in …

Podophyllotoxin is the natural product precursor of the chemotherapeutic etoposide, yet only
part of its biosynthetic pathway is known. We used transcriptome mining in Podophyllum …

As a major component of plant specialized metabolism, phenylpropanoid biosynthetic
pathways provide anthocyanins for pigmentation, flavonoids such as flavones for protection …

Dirigent (DIR) proteins were found to mediate regio-and stereoselectivity of bimolecular
phenoxy radical coupling during lignan biosynthesis. Here we summarize the current …

Plants, marine organisms, and microorganisms have evolved complex chemical defense
and signaling systems that are designed to protect them from predators and provide other …

The metabolism of the plant lignans matairesinol, secoisolariciresinol, pinoresinol,
syringaresinol, arctigenin, 7-hydroxymatairesinol, isolariciresinol, and lariciresinol by human …

In nature, chiral natural products are usually produced in optically pure form—however,
occasionally both enantiomers are formed. These enantiomeric natural products can arise …

Phenylpropenes such as chavicol, t-anol, eugenol, and isoeugenol are produced by plants
as defense compounds against animals and microorganisms and as floral attractants of …

Lignans are phenylpropanoid dimers, where the phenylpropane units are linked by the
central carbon (C8) of their side chains. Ligans vary substantially in oxidation level …