Melatonin modulates the circadian rhythm and has been studied as a preventive measure
against the development of delirium in hospitalized patients. Such an effect may be more …

Stroke remains one of the leading causes of long-term disability and mortality despite recent
advances in acute thrombolytic therapies. In fact, the global lifetime risk of stroke in adults …

Objectives: To evaluate whether the use of exogenous melatonin affects sleep, reduces the
prevalence of delirium, and decreases the need for analgosedation and to assess whether …

Background Respiratory distress requiring intubation is the most serious complication
associated with coronavirus disease 2019 (COVID-19). Methods In this retrospective study …

To investigate the efficacy of exogenous administration of melatonin and melatonin receptor
agonists for the improvement of delirium, sleep, and other clinical outcomes of subjects in …

Aim The intensive care unit (ICU) environment contributes to the development of sleep
disturbances. Sleep disturbances, sleep fragmentation, and multiple awakening episodes …

Patients with COVID-19 have shown melatonin deficiency. We evaluated the efficacy and
safety of administration oral melatonin in patients with COVID-19-induced pneumonia …

Background Melatonin might be beneficial to coronavirus disease 2019 (COVID-19) patients
in terms of both prevention and treatment. We investigated how melatonin affected various …

Background: Hyperglycemia is a common finding which is associated with increased
mortality and morbidity among critically ill patients. There is currently no evidence that …

There is a lack of effective therapies for stroke patients; its treatment is even more difficult
considering the unexpected onset of the disease. In the last decade, melatonin has emerged …