The vast opportunities for biomaterials design and functionality enabled by mimicking nature
continue to stretch the limits of imagination. As both biological understanding and …

Cryo-electron tomography (cryo-ET) allows 3D volumes to be reconstructed from a set of 2D
projection images of a tilted biological sample. It allows densities to be resolved in 3D that …

Following the Ebola virus disease epidemic in west Africa, there has been increased
awareness of the need for improved therapies for emerging diseases, including viral …

Ebola and Marburg viruses are filoviruses: filamentous, enveloped viruses that cause
haemorrhagic fever. Filoviruses are within the order Mononegavirales, which also includes …

Inclusion bodies are a characteristic feature of ebolavirus infections in cells. They contain
large numbers of preformed nucleocapsids, but their biological significance has been …

Ebola virus causes haemorrhagic fever with a high fatality rate in humans and non-human
primates. It belongs to the family Filoviridae in the order Mononegavirales, which are viruses …

Ebola virus (EBOV), member of genus Ebolavirus, family Filoviridae, have a non-segmented,
single-stranded RNA that contains seven genes:(a) nucleoprotein (NP),(b) viral protein 35 …

During viral RNA synthesis, Ebola virus (EBOV) nucleoprotein (NP) alternates between an
RNA-template-bound form and a template-free form to provide the viral polymerase access …

Work with infectious Ebola viruses is restricted to biosafety level 4 (BSL4) laboratories,
presenting a significant barrier for studying these viruses. Life cycle modeling systems …

Nucleocapsid (N) encoded by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) plays key roles in the replication cycle and is a critical serological marker. Here, we …