Quantitative susceptibility mapping (QSM): decoding MRI data for a tissue magnetic biomarker
In MRI, the main magnetic field polarizes the electron cloud of a molecule, generating a
chemical shift for observer protons within the molecule and a magnetic susceptibility …
chemical shift for observer protons within the molecule and a magnetic susceptibility …
Cerebral oxygen extraction fraction MRI: Techniques and applications
The human brain constitutes 2% of the body's total mass but uses 20% of the oxygen. The
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …
Gibbs ringing in diffusion MRI
Purpose To study and reduce the effect of Gibbs ringing artifact on computed diffusion
parameters. Methods We reduce the ringing by extrapolating the k‐space of each diffusion …
parameters. Methods We reduce the ringing by extrapolating the k‐space of each diffusion …
Improved estimation of myelin water fraction using complex model fitting
In gradient echo (GRE) imaging, three compartment water modeling (myelin water, axonal
water and extracellular water) in white matter has been demonstrated to show different …
water and extracellular water) in white matter has been demonstrated to show different …
Susceptibility source separation from gradient echo data using magnitude decay modeling
Abstract Background and Purpose The objective is to demonstrate feasibility of separating
magnetic sources in quantitative susceptibility mapping (QSM) by incorporating magnitude …
magnetic sources in quantitative susceptibility mapping (QSM) by incorporating magnitude …
Cerebral metabolic rate of oxygen (CMRO2) mapping by combining quantitative susceptibility mapping (QSM) and quantitative blood oxygenation level‐dependent …
Purpose To map the cerebral metabolic rate of oxygen (CMRO2) by estimating the oxygen
extraction fraction (OEF) from gradient echo imaging (GRE) using phase and magnitude of …
extraction fraction (OEF) from gradient echo imaging (GRE) using phase and magnitude of …
Advanced MRI unravels the nature of tissue alterations in early multiple sclerosis
G Bonnier, A Roche, D Romascano… - Annals of clinical …, 2014 - Wiley Online Library
Introduction In patients with multiple sclerosis (MS), conventional magnetic resonance
imaging (MRI) provides only limited insights into the nature of brain damage with modest …
imaging (MRI) provides only limited insights into the nature of brain damage with modest …
In vivo detection of microstructural correlates of brain pathology in preclinical and early Alzheimer Disease with magnetic resonance imaging
Background Alzheimer disease (AD) affects at least 5 million individuals in the USA alone
stimulating an intense search for disease prevention and treatment therapies as well as for …
stimulating an intense search for disease prevention and treatment therapies as well as for …
Separation of cellular and BOLD contributions to T2* signal relaxation
X Ulrich, DA Yablonskiy - Magnetic resonance in medicine, 2016 - Wiley Online Library
Purpose The development of a reliable clinical technique for quantitative measurements of
the parameters defining the BOLD effect, ie, oxygen extraction fraction (OEF), and …
the parameters defining the BOLD effect, ie, oxygen extraction fraction (OEF), and …
Magnetic susceptibility source separation solely from gradient echo data: histological validation
Quantitative susceptibility mapping (QSM) facilitates mapping of the bulk magnetic
susceptibility of tissue from the phase of complex gradient echo (GRE) MRI data. QSM …
susceptibility of tissue from the phase of complex gradient echo (GRE) MRI data. QSM …