Background Oral cancer causes significant morbidity and mortality. Chemoprevention
utilizes medication or natural compounds to reverse oral premalignant lesions and to …

Nuclear factor-kappa B (NF-κB) transcription factors regulate cellular processes such as
inflammation and cell survival. The NF-κB pathway is often activated with development and …

Oral cancer is often painful and lethal. Oral cancer progression and pain may result from
shared pathways that involve unresolved inflammation and elevated levels of pro …

Epidermal growth factor receptor (EGFR) and COX-2 inhibitors synergistically inhibit head
and neck squamous cell carcinoma tumorigenesis in preclinical studies. We conducted a …

The concept of chemoprevention whereby the use of a systemic agent is intended to halt the
carcinogenesis process has been an attractive topic in head and neck squamous cell …

Dysplasia affecting the oral mucosa has a malignant potential. The options for treatment of
oral dysplasia are limited. Surgery remains the mainstay of management, with no strong …

Precancerous cells in the oral cavity may appear as oral potentially malignant disorders, but
they may also present as dysplasia without visual manifestation in tumor-adjacent tissue. As …

Cancers of the head and neck region are among the leading causes of cancer-related
mortalities worldwide. Oral leukoplakia and erythroplakia are identified as precursor lesions …

Simple Summary Oral cancer is a devastating disease with increasing incidence worldwide.
Oral epithelial dysplasia (OED) is a potentially malignant disorder and patients with OED are …

The article focuses on the risk factors and prevention or interventions of oral squamous cell
carcinoma. It says that various risk factors are associated with the oral cancer and precursor …